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Phase 2a Safety, Pharmacokinetics, and Acceptability of Dapivirine Vaginal Rings in US Postmenopausal Women.
Chen BA, Zhang J, Gundacker HM, Hendrix CW, Hoesley CJ, Salata RA, Dezzutti CS, van der Straten A, Hall WB, Jacobson CE, Johnson S, McGowan I, Nel AM, Soto-Torres L, Marzinke MA; MTN-024/IPM 031 Protocol Team for the Microbicide Trials Network. Chen BA, et al. Among authors: mcgowan i. Clin Infect Dis. 2019 Mar 19;68(7):1144-1151. doi: 10.1093/cid/ciy654. Clin Infect Dis. 2019. PMID: 30289485 Free PMC article. Clinical Trial.
"Tell Juliana": acceptability of the candidate microbicide VivaGel® and two placebo gels among ethnically diverse, sexually active young women participating in a phase 1 microbicide study.
Carballo-Diéguez A, Giguere R, Dolezal C, Chen BA, Kahn J, Zimet G, Mabragaña M, Leu CS, McGowan I. Carballo-Diéguez A, et al. Among authors: mcgowan i. AIDS Behav. 2012 Oct;16(7):1761-74. doi: 10.1007/s10461-011-0028-6. AIDS Behav. 2012. PMID: 21863338 Free PMC article. Clinical Trial.
RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate.
Anton PA, Cranston RD, Kashuba A, Hendrix CW, Bumpus NN, Richardson-Harman N, Elliott J, Janocko L, Khanukhova E, Dennis R, Cumberland WG, Ju C, Carballo-Diéguez A, Mauck C, McGowan I. Anton PA, et al. Among authors: mcgowan i. AIDS Res Hum Retroviruses. 2012 Nov;28(11):1412-21. doi: 10.1089/aid.2012.0262. Epub 2012 Oct 9. AIDS Res Hum Retroviruses. 2012. PMID: 22943559 Free PMC article. Clinical Trial.
Rectal microbicide development.
McGowan I, Dezzutti C. McGowan I, et al. Curr Top Microbiol Immunol. 2014;383:117-36. doi: 10.1007/82_2013_325. Curr Top Microbiol Immunol. 2014. PMID: 23612991 Free PMC article. Review.
A multi-compartment single and multiple dose pharmacokinetic comparison of rectally applied tenofovir 1% gel and oral tenofovir disoproxil fumarate.
Yang KH, Hendrix C, Bumpus N, Elliott J, Tanner K, Mauck C, Cranston R, McGowan I, Richardson-Harman N, Anton PA, Kashuba AD. Yang KH, et al. Among authors: mcgowan i. PLoS One. 2014 Oct 28;9(10):e106196. doi: 10.1371/journal.pone.0106196. eCollection 2014. PLoS One. 2014. PMID: 25350119 Free PMC article. Clinical Trial.
158 results