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Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease.
Abramowitz MK, Paredes W, Zhang K, Brightwell CR, Newsom JN, Kwon HJ, Custodio M, Buttar RS, Farooq H, Zaidi B, Pai R, Pessin JE, Hawkins M, Fry CS. Abramowitz MK, et al. Among authors: pessin je. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1658-F1669. doi: 10.1152/ajprenal.00314.2018. Epub 2018 Oct 3. Am J Physiol Renal Physiol. 2018. PMID: 30280599 Free PMC article.
Muscle fibrosis and maladaptation occur progressively in CKD and are rescued by dialysis.
Brightwell CR, Kulkarni AS, Paredes W, Zhang K, Perkins JB, Gatlin KJ, Custodio M, Farooq H, Zaidi B, Pai R, Buttar RS, Tang Y, Melamed ML, Hostetter TH, Pessin JE, Hawkins M, Fry CS, Abramowitz MK. Brightwell CR, et al. Among authors: pessin je. JCI Insight. 2021 Dec 22;6(24):e150112. doi: 10.1172/jci.insight.150112. JCI Insight. 2021. PMID: 34784301 Free PMC article.
Adipokines mediate inflammation and insulin resistance.
Kwon H, Pessin JE. Kwon H, et al. Among authors: pessin je. Front Endocrinol (Lausanne). 2013 Jun 12;4:71. doi: 10.3389/fendo.2013.00071. eCollection 2013. Front Endocrinol (Lausanne). 2013. PMID: 23781214 Free PMC article.
310 results