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SAR of 4-Alkoxybenzoic Acid Inhibitors of the Trypanosome Alternative Oxidase.
Meco-Navas A, Ebiloma GU, Martín-Domínguez A, Martínez-Benayas I, Cueto-Díaz EJ, Alhejely AS, Balogun EO, Saito M, Matsui M, Arai N, Shiba T, Harada S, de Koning HP, Dardonville C. Meco-Navas A, et al. Among authors: dardonville c. ACS Med Chem Lett. 2018 Jul 31;9(9):923-928. doi: 10.1021/acsmedchemlett.8b00282. eCollection 2018 Sep 13. ACS Med Chem Lett. 2018. PMID: 30258542 Free PMC article.
In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27.
Acosta-Reyes FJ, Dardonville C, de Koning HP, Natto M, Subirana JA, Campos JL. Acosta-Reyes FJ, et al. Among authors: dardonville c. Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1614-21. doi: 10.1107/S139900471400697X. Epub 2014 May 24. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24914972 Free PMC article.
A new nonpolar N-hydroxy imidazoline lead compound with improved activity in a murine model of late-stage Trypanosoma brucei brucei infection is not cross-resistant with diamidines.
Ríos Martínez CH, Miller F, Ganeshamoorthy K, Glacial F, Kaiser M, de Koning HP, Eze AA, Lagartera L, Herraiz T, Dardonville C. Ríos Martínez CH, et al. Among authors: dardonville c. Antimicrob Agents Chemother. 2015 Feb;59(2):890-904. doi: 10.1128/AAC.03958-14. Epub 2014 Nov 24. Antimicrob Agents Chemother. 2015. PMID: 25421467 Free PMC article.
Antiprotozoal activity and DNA binding of dicationic acridones.
Montalvo-Quirós S, Taladriz-Sender A, Kaiser M, Dardonville C. Montalvo-Quirós S, et al. Among authors: dardonville c. J Med Chem. 2015 Feb 26;58(4):1940-9. doi: 10.1021/jm5018303. Epub 2015 Feb 16. J Med Chem. 2015. PMID: 25642604
47 results