Sadler PJ - Search Results

1

In Vivo Selectivity and Localization of Reactive Oxygen Species (ROS) Induction by Osmium Anticancer Complexes That Circumvent Platinum Resistance.

Coverdale JPC, Bridgewater HE, Song JI, Smith NA, Barry NPE, Bagley I, Sadler PJ, Romero-Canelón I. Coverdale JPC, et al. Among authors: sadler pj. J Med Chem. 2018 Oct 25;61(20):9246-9255. doi: 10.1021/acs.jmedchem.8b00958. Epub 2018 Oct 5. J Med Chem. 2018. PMID: 30230827 Free PMC article.

2

Inhibition of cancer cell growth by ruthenium(II) arene complexes.

Morris RE, Aird RE, Murdoch Pdel S, Chen H, Cummings J, Hughes ND, Parsons S, Parkin A, Boyd G, Jodrell DI, Sadler PJ. Morris RE, et al. Among authors: sadler pj. J Med Chem. 2001 Oct 25;44(22):3616-21. doi: 10.1021/jm010051m. J Med Chem. 2001. PMID: 11606126

3

Light-activated destruction of cancer cell nuclei by platinum diazide complexes.

Bednarski PJ, Grünert R, Zielzki M, Wellner A, Mackay FS, Sadler PJ. Bednarski PJ, et al. Among authors: sadler pj. Chem Biol. 2006 Jan;13(1):61-7. doi: 10.1016/j.chembiol.2005.10.011. Chem Biol. 2006. PMID: 16426972

4

Structure-activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands.

Habtemariam A, Melchart M, Fernandez R, Parsons S, Oswald ID, Parkin A, Fabbiani FP, Davidson JE, Dawson A, Aird RE, Jodrell DI, Sadler PJ. Habtemariam A, et al. Among authors: sadler pj. J Med Chem. 2006 Nov 16;49(23):6858-68. doi: 10.1021/jm060596m. J Med Chem. 2006. PMID: 17154516

5

Photoactivatable platinum complexes.

Bednarski PJ, Mackay FS, Sadler PJ. Bednarski PJ, et al. Among authors: sadler pj. Anticancer Agents Med Chem. 2007 Jan;7(1):75-93. doi: 10.2174/187152007779314053. Anticancer Agents Med Chem. 2007. PMID: 17266506 Review.

6

New trends for metal complexes with anticancer activity.

Bruijnincx PC, Sadler PJ. Bruijnincx PC, et al. Among authors: sadler pj. Curr Opin Chem Biol. 2008 Apr;12(2):197-206. doi: 10.1016/j.cbpa.2007.11.013. Epub 2008 Jan 25. Curr Opin Chem Biol. 2008. PMID: 18155674 Free PMC article. Review.

7

DNA interactions of monofunctional organometallic osmium(II) antitumor complexes in cell-free media.

Kostrhunova H, Florian J, Novakova O, Peacock AF, Sadler PJ, Brabec V. Kostrhunova H, et al. Among authors: sadler pj. J Med Chem. 2008 Jun 26;51(12):3635-43. doi: 10.1021/jm701538w. J Med Chem. 2008. PMID: 18494458

8

Cytotoxicity, cellular uptake, and DNA interactions of new monodentate ruthenium(II) complexes containing terphenyl arenes.

Bugarcic T, Nováková O, Halámiková A, Zerzánková L, Vrána O, Kaspárková J, Habtemariam A, Parsons S, Sadler PJ, Brabec V. Bugarcic T, et al. Among authors: sadler pj. J Med Chem. 2008 Sep 11;51(17):5310-9. doi: 10.1021/jm8003043. Epub 2008 Aug 14. J Med Chem. 2008. PMID: 18702458

9

Medicinal organometallic chemistry: designing metal arene complexes as anticancer agents.

Peacock AF, Sadler PJ. Peacock AF, et al. Among authors: sadler pj. Chem Asian J. 2008 Nov 13;3(11):1890-9. doi: 10.1002/asia.200800149. Chem Asian J. 2008. PMID: 18712745 Free article. Review.

10

Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives.

van Rijt SH, Peacock AF, Johnstone RD, Parsons S, Sadler PJ. van Rijt SH, et al. Among authors: sadler pj. Inorg Chem. 2009 Feb 16;48(4):1753-62. doi: 10.1021/ic8020222. Inorg Chem. 2009. PMID: 19146436

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