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mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease.
Ast A, Buntru A, Schindler F, Hasenkopf R, Schulz A, Brusendorf L, Klockmeier K, Grelle G, McMahon B, Niederlechner H, Jansen I, Diez L, Edel J, Boeddrich A, Franklin SA, Baldo B, Schnoegl S, Kunz S, Purfürst B, Gaertner A, Kampinga HH, Morton AJ, Petersén Å, Kirstein J, Bates GP, Wanker EE. Ast A, et al. Among authors: klockmeier k. Mol Cell. 2018 Sep 6;71(5):675-688.e6. doi: 10.1016/j.molcel.2018.07.032. Mol Cell. 2018. PMID: 30193095 Free article.
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke M, Bounab Y, Strempel N, Klockmeier K, Yigit S, Friedrich RP, Chaurasia G, Li S, Hesse F, Riechers SP, Russ J, Nicoletti C, Boeddrich A, Wiglenda T, Haenig C, Schnoegl S, Fournier D, Graham RK, Hayden MR, Sigrist S, Bates GP, Priller J, Andrade-Navarro MA, Futschik ME, Wanker EE. Stroedicke M, et al. Among authors: klockmeier k. Genome Res. 2015 May;25(5):701-13. doi: 10.1101/gr.182444.114. Genome Res. 2015. PMID: 25908449 Free PMC article.
Self-assembly of Mutant Huntingtin Exon-1 Fragments into Large Complex Fibrillar Structures Involves Nucleated Branching.
Wagner AS, Politi AZ, Ast A, Bravo-Rodriguez K, Baum K, Buntru A, Strempel NU, Brusendorf L, Hänig C, Boeddrich A, Plassmann S, Klockmeier K, Ramirez-Anguita JM, Sanchez-Garcia E, Wolf J, Wanker EE. Wagner AS, et al. Among authors: klockmeier k. J Mol Biol. 2018 Jun 8;430(12):1725-1744. doi: 10.1016/j.jmb.2018.03.017. Epub 2018 Mar 28. J Mol Biol. 2018. PMID: 29601786 Free article.
Current Approaches Toward Quantitative Mapping of the Interactome.
Buntru A, Trepte P, Klockmeier K, Schnoegl S, Wanker EE. Buntru A, et al. Among authors: klockmeier k. Front Genet. 2016 May 4;7:74. doi: 10.3389/fgene.2016.00074. eCollection 2016. Front Genet. 2016. PMID: 27200083 Free PMC article.
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, Secker C, Diez L, Schulz A, Klockmeier K, Zenkner M, Golusik S, Rau K, Schnoegl S, Garner CC, Wanker EE. Trepte P, et al. Among authors: klockmeier k. Mol Syst Biol. 2018 Jul 11;14(7):e8071. doi: 10.15252/msb.20178071. Mol Syst Biol. 2018. PMID: 29997244 Free PMC article.