Chen Z - Search Results

1

Synthesis, pharmacology and preclinical evaluation of ¹¹C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein.

Chen Z, Mori W, Zhang X, Yamasaki T, Dunn PJ, Zhang G, Fu H, Shao T, Zhang Y, Hatori A, Ma L, Fujinaga M, Xie L, Deng X, Li H, Yu Q, Rong J, Josephson L, Ma JA, Shao Y, Tomita S, Zhang MR, Liang SH. Chen Z, et al. Eur J Med Chem. 2018 Sep 5;157:898-908. doi: 10.1016/j.ejmech.2018.08.019. Epub 2018 Aug 9. Eur J Med Chem. 2018. PMID: 30145376 Free PMC article.

2

Copper-catalyzed one-pot denitrogenative-dehydrogenative-decarboxylative coupling of β-ketoacids with trifluorodiazoethane: facile access to trifluoromethylated aldol products.

Xiong HY, Yang ZY, Chen Z, Zeng JL, Nie J, Ma JA. Xiong HY, et al. Among authors: chen z. Chemistry. 2014 Jul 1;20(27):8325-9. doi: 10.1002/chem.201403073. Epub 2014 May 30. Chemistry. 2014. PMID: 24889186

3

Silver-catalyzed regioselective [3+2] cycloaddition of arene-diazonium salts with 2,2,2-trifluorodiazoethane (CF3CHN2): a facile access to 2-aryl-5-trifluoromethyltetrazoles.

Chen Z, Fan SQ, Zheng Y, Ma JA. Chen Z, et al. Chem Commun (Camb). 2015 Nov 28;51(92):16545-8. doi: 10.1039/c5cc07324c. Chem Commun (Camb). 2015. PMID: 26419899

4

Use of a Traceless Activating and Directing Group for the Construction of Trifluoromethylpyrazoles: One-Pot Transformation of Nitroolefins and Trifluorodiazoethane.

Chen Z, Zheng Y, Ma JA. Chen Z, et al. Angew Chem Int Ed Engl. 2017 Apr 10;56(16):4569-4574. doi: 10.1002/anie.201700955. Epub 2017 Mar 22. Angew Chem Int Ed Engl. 2017. PMID: 28328171

5

Metal Protein-Attenuating Compound for PET Neuroimaging: Synthesis and Preclinical Evaluation of [¹¹C]PBT2.

Krishnan HS, Bernard-Gauthier V, Placzek MS, Dahl K, Narayanaswami V, Livni E, Chen Z, Yang J, Collier TL, Ran C, Hooker JM, Liang SH, Vasdev N. Krishnan HS, et al. Among authors: chen z. Mol Pharm. 2018 Feb 5;15(2):695-702. doi: 10.1021/acs.molpharmaceut.7b00936. Epub 2018 Jan 22. Mol Pharm. 2018. PMID: 29298483

6

In Vitro and in Vivo Evaluation of ¹¹C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.

Cheng R, Mori W, Ma L, Alhouayek M, Hatori A, Zhang Y, Ogasawara D, Yuan G, Chen Z, Zhang X, Shi H, Yamasaki T, Xie L, Kumata K, Fujinaga M, Nagai Y, Minamimoto T, Svensson M, Wang L, Du Y, Ondrechen MJ, Vasdev N, Cravatt BF, Fowler C, Zhang MR, Liang SH. Cheng R, et al. Among authors: chen z. J Med Chem. 2018 Mar 22;61(6):2278-2291. doi: 10.1021/acs.jmedchem.7b01400. Epub 2018 Mar 9. J Med Chem. 2018. PMID: 29481079 Free PMC article.

7

Transition-Metal-Free [3 + 2] Cycloaddition of Nitroolefins and Diazoacetonitrile: A Facile Access to Multisubstituted Cyanopyrazoles.

Chen Z, Zhang Y, Nie J, Ma JA. Chen Z, et al. Org Lett. 2018 Apr 6;20(7):2120-2124. doi: 10.1021/acs.orglett.8b00729. Epub 2018 Mar 26. Org Lett. 2018. PMID: 29578724

8

Direct Regioselective [3 + 2] Cycloaddition Reactions of Masked Difluorodiazoethane with Electron-Deficient Alkynes and Alkenes: Synthesis of Difluoromethyl-Substituted Pyrazoles.

Zeng JL, Chen Z, Zhang FG, Ma JA. Zeng JL, et al. Among authors: chen z. Org Lett. 2018 Aug 3;20(15):4562-4565. doi: 10.1021/acs.orglett.8b01854. Epub 2018 Jul 17. Org Lett. 2018. PMID: 30014703

9

Ru-Photoredox-Catalyzed Decarboxylative Oxygenation of Aliphatic Carboxylic Acids through N-(acyloxy)phthalimide.

Zheng C, Wang Y, Xu Y, Chen Z, Chen G, Liang SH. Zheng C, et al. Among authors: chen z, chen g. Org Lett. 2018 Aug 17;20(16):4824-4827. doi: 10.1021/acs.orglett.8b01885. Epub 2018 Aug 2. Org Lett. 2018. PMID: 30070856

10

Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-Methyl-d-aspartate (NMDA), α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Receptors.

Fu H, Chen Z, Josephson L, Li Z, Liang SH. Fu H, et al. Among authors: chen z. J Med Chem. 2019 Jan 24;62(2):403-419. doi: 10.1021/acs.jmedchem.8b00714. Epub 2018 Aug 27. J Med Chem. 2019. PMID: 30110164 Free PMC article. Review.

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