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Induced Pluripotent Stem Cell-Derived Podocyte-Like Cells as Models for Assessing Mechanisms Underlying Heritable Disease Phenotype: Initial Studies Using Two Alport Syndrome Patient Lines Indicate Impaired Potassium Channel Activity.
J Pharmacol Exp Ther. 2018 Nov;367(2):335-347. doi: 10.1124/jpet.118.250142. Epub 2018 Aug 13.
J Pharmacol Exp Ther. 2018.
PMID: 30104322
A CX3CR1 Reporter hESC Line Facilitates Integrative Analysis of In-Vitro-Derived Microglia and Improved Microglia Identity upon Neuron-Glia Co-culture.
Grubman A, Vandekolk TH, Schröder J, Sun G, Hatwell-Humble J, Chan J, Oksanen M, Lehtonen S, Hunt C, Koistinaho JE, Nilsson SK, Haynes JM, Pouton CW, Polo JM.
Grubman A, et al. Among authors: vandekolk th.
Stem Cell Reports. 2020 Jun 9;14(6):1018-1032. doi: 10.1016/j.stemcr.2020.04.007. Epub 2020 May 21.
Stem Cell Reports. 2020.
PMID: 32442534
Free PMC article.
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Transcriptional signature in microglia associated with Aβ plaque phagocytosis.
Grubman A, Choo XY, Chew G, Ouyang JF, Sun G, Croft NP, Rossello FJ, Simmons R, Buckberry S, Landin DV, Pflueger J, Vandekolk TH, Abay Z, Zhou Y, Liu X, Chen J, Larcombe M, Haynes JM, McLean C, Williams S, Chai SY, Wilson T, Lister R, Pouton CW, Purcell AW, Rackham OJL, Petretto E, Polo JM.
Grubman A, et al. Among authors: vandekolk th.
Nat Commun. 2021 May 21;12(1):3015. doi: 10.1038/s41467-021-23111-1.
Nat Commun. 2021.
PMID: 34021136
Free PMC article.
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Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors.
Merlin J, Park J, Vandekolk TH, Fabb SA, Allinne J, Summers RJ, Langmead CJ, Riddy DM.
Merlin J, et al. Among authors: vandekolk th.
Mol Pharmacol. 2022 Apr;101(4):246-256. doi: 10.1124/molpharm.121.000422. Epub 2022 Feb 6.
Mol Pharmacol. 2022.
PMID: 35125345
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Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia.
Hatzipantelis CJ, Langiu M, Vandekolk TH, Pierce TL, Nithianantharajah J, Stewart GD, Langmead CJ.
Hatzipantelis CJ, et al. Among authors: vandekolk th.
ACS Pharmacol Transl Sci. 2020 Oct 28;3(6):1042-1062. doi: 10.1021/acsptsci.0c00117. eCollection 2020 Dec 11.
ACS Pharmacol Transl Sci. 2020.
PMID: 33344888
Free PMC article.
Review.
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Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor.
Johnson RM, Zhang X, Piper SJ, Nettleton TJ, Vandekolk TH, Langmead CJ, Danev R, Sexton PM, Wootten D.
Johnson RM, et al. Among authors: vandekolk th.
Biochem Biophys Res Commun. 2021 Nov 12;578:84-90. doi: 10.1016/j.bbrc.2021.09.016. Epub 2021 Sep 16.
Biochem Biophys Res Commun. 2021.
PMID: 34547628
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