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A novel JAK-STAT inhibitor, 2-[(3-Carbamoyl-2-thienyl)amino]-2-oxoethyl(2,6-dichlorophenyl)acetate, suppresses helper T cell differentiation in vitro and collagen-induced arthritis in vivo.
Asakawa M, Yoshida H, Sakai R, Saeki K, Okada M, Kanamori M, Kotani H, Wei X, Yoshimura A. Asakawa M, et al. Among authors: saeki k. Biochem Biophys Res Commun. 2015 Dec 25;468(4):766-73. doi: 10.1016/j.bbrc.2015.11.030. Epub 2015 Nov 10. Biochem Biophys Res Commun. 2015. PMID: 26562526
CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion.
Nakamura Y, Kanai T, Saeki K, Takabe M, Irie J, Miyoshi J, Mikami Y, Teratani T, Suzuki T, Miyata N, Hisamatsu T, Nakamoto N, Yamagishi Y, Higuchi H, Ebinuma H, Hozawa S, Saito H, Itoh H, Hibi T. Nakamura Y, et al. Among authors: saeki k. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 15;304(8):G700-7. doi: 10.1152/ajpgi.00318.2012. Epub 2013 Feb 28. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23449669 Free article.
1,072 results