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Small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity represents a potential strategy for anticancer therapy.
Gervais V, Muller I, Mari PO, Mourcet A, Movellan KT, Ramos P, Marcoux J, Guillet V, Javaid S, Burlet-Schiltz O, Czaplicki G, Milon A, Giglia-Mari G. Gervais V, et al. Among authors: mari po. J Biol Chem. 2018 Sep 28;293(39):14974-14988. doi: 10.1074/jbc.RA118.003444. Epub 2018 Aug 1. J Biol Chem. 2018. PMID: 30068551 Free PMC article.
In vivo interactions of TTDA mutant proteins within TFIIH.
Nonnekens J, Cabantous S, Slingerland J, Mari PO, Giglia-Mari G. Nonnekens J, et al. Among authors: mari po. J Cell Sci. 2013 Aug 1;126(Pt 15):3278-83. doi: 10.1242/jcs.126839. Epub 2013 May 31. J Cell Sci. 2013. PMID: 23729738
ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair.
Mourgues S, Gautier V, Lagarou A, Bordier C, Mourcet A, Slingerland J, Kaddoum L, Coin F, Vermeulen W, Gonzales de Peredo A, Monsarrat B, Mari PO, Giglia-Mari G. Mourgues S, et al. Among authors: mari po. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17927-32. doi: 10.1073/pnas.1305009110. Epub 2013 Oct 14. Proc Natl Acad Sci U S A. 2013. PMID: 24127601 Free PMC article.
A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair.
Ranes M, Boeing S, Wang Y, Wienholz F, Menoni H, Walker J, Encheva V, Chakravarty P, Mari PO, Stewart A, Giglia-Mari G, Snijders AP, Vermeulen W, Svejstrup JQ. Ranes M, et al. Among authors: mari po. Nucleic Acids Res. 2016 Jun 20;44(11):5246-55. doi: 10.1093/nar/gkw216. Epub 2016 Apr 7. Nucleic Acids Res. 2016. PMID: 27060134 Free PMC article.
27 results