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Ablation of soluble epoxide hydrolase reprogram white fat to beige-like fat through an increase in mitochondrial integrity, HO-1-adiponectin in vitro and in vivo.
Liu L, Puri N, Raffaele M, Schragenheim J, Singh SP, Bradbury JA, Bellner L, Vanella L, Zeldin DC, Cao J, Abraham NG. Liu L, et al. Among authors: abraham ng. Prostaglandins Other Lipid Mediat. 2018 Sep;138:1-8. doi: 10.1016/j.prostaglandins.2018.07.004. Epub 2018 Jul 21. Prostaglandins Other Lipid Mediat. 2018. PMID: 30041041 Free PMC article.
Oxidized HDL is a potent inducer of adipogenesis and causes activation of the Ang-II and 20-HETE systems in human obese females.
Peterson SJ, Vanella L, Gotlinger K, Jiang H, Singh SP, Sodhi K, Maher E, O'Hanlon K, Shapiro JI, Abraham NG. Peterson SJ, et al. Among authors: abraham ng. Prostaglandins Other Lipid Mediat. 2016 Mar;123:68-77. doi: 10.1016/j.prostaglandins.2016.04.004. Epub 2016 May 11. Prostaglandins Other Lipid Mediat. 2016. PMID: 27179555 Review.
EET enhances renal function in obese mice resulting in restoration of HO-1-Mfn1/2 signaling, and decrease in hypertension through inhibition of sodium chloride co-transporter.
Schragenheim J, Bellner L, Cao J, Singh SP, Bamshad D, McClung JA, Maayan O, Meissner A, Grant I, Stier CT Jr, Abraham NG. Schragenheim J, et al. Among authors: abraham ng. Prostaglandins Other Lipid Mediat. 2018 Jul;137:30-39. doi: 10.1016/j.prostaglandins.2018.05.008. Epub 2018 May 19. Prostaglandins Other Lipid Mediat. 2018. PMID: 29787809 Free PMC article.
Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells.
Kim DH, Burgess AP, Li M, Tsenovoy PL, Addabbo F, McClung JA, Puri N, Abraham NG. Kim DH, et al. Among authors: abraham ng. J Pharmacol Exp Ther. 2008 Jun;325(3):833-40. doi: 10.1124/jpet.107.135285. Epub 2008 Mar 11. J Pharmacol Exp Ther. 2008. PMID: 18334666
Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ.
Kim DH, Vanella L, Inoue K, Burgess A, Gotlinger K, Manthati VL, Koduru SR, Zeldin DC, Falck JR, Schwartzman ML, Abraham NG. Kim DH, et al. Among authors: abraham ng. Stem Cells Dev. 2010 Dec;19(12):1863-73. doi: 10.1089/scd.2010.0098. Epub 2010 Oct 9. Stem Cells Dev. 2010. PMID: 20412023 Free PMC article.
389 results