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Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat Struct Mol Biol. 2018 Jul;25(7):591-600. doi: 10.1038/s41594-018-0083-z. Epub 2018 Jul 2.
Nat Struct Mol Biol. 2018.
PMID: 29967538
Free PMC article.
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D.
Drané P, et al. Among authors: parnandi n.
Nature. 2017 Mar 9;543(7644):211-216. doi: 10.1038/nature21358. Epub 2017 Feb 27.
Nature. 2017.
PMID: 28241136
Free PMC article.
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TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.
Parnandi N, Rendo V, Cui G, Botuyan MV, Remisova M, Nguyen H, Drané P, Beroukhim R, Altmeyer M, Mer G, Chowdhury D.
Parnandi N, et al.
Mol Cell. 2021 Jun 17;81(12):2583-2595.e6. doi: 10.1016/j.molcel.2021.03.039. Epub 2021 May 6.
Mol Cell. 2021.
PMID: 33961797
Free PMC article.
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Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance-Computed Tomography Image Guided Radiation Therapy.
Detappe A, Thomas E, Tibbitt MW, Kunjachan S, Zavidij O, Parnandi N, Reznichenko E, Lux F, Tillement O, Berbeco R.
Detappe A, et al. Among authors: parnandi n.
Nano Lett. 2017 Mar 8;17(3):1733-1740. doi: 10.1021/acs.nanolett.6b05055. Epub 2017 Feb 2.
Nano Lett. 2017.
PMID: 28145723
Free PMC article.
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Correction to "Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance-Computed Tomography Image Guided Radiation Therapy".
Detappe A, Thomas E, Tibbitt MW, Kunjachan S, Zavidij O, Parnandi N, Reznichenko E, Lux F, Tillement O, Berbeco R.
Detappe A, et al. Among authors: parnandi n.
Nano Lett. 2020 Aug 12;20(8):6223. doi: 10.1021/acs.nanolett.0c02961. Epub 2020 Jul 28.
Nano Lett. 2020.
PMID: 32787190
No abstract available.
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Negative DNA supercoiling induces genome-wide Cas9 off-target activity.
Newton MD, Losito M, Smith QM, Parnandi N, Taylor BJ, Akcakaya P, Maresca M, van Eijk P, Reed SH, Boulton SJ, King GA, Cuomo ME, Rueda DS.
Newton MD, et al. Among authors: parnandi n.
Mol Cell. 2023 Oct 5;83(19):3533-3545.e5. doi: 10.1016/j.molcel.2023.09.008.
Mol Cell. 2023.
PMID: 37802026
Free article.
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