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Contribution of the macrophage migration inhibitory factor superfamily of cytokines in the pathogenesis of preclinical and human multiple sclerosis: In silico and in vivo evidences.
Fagone P, Mazzon E, Cavalli E, Bramanti A, Petralia MC, Mangano K, Al-Abed Y, Bramati P, Nicoletti F. Fagone P, et al. Among authors: mangano k. J Neuroimmunol. 2018 Sep 15;322:46-56. doi: 10.1016/j.jneuroim.2018.06.009. Epub 2018 Jun 15. J Neuroimmunol. 2018. PMID: 29935880 Free article.
Activation of group III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures.
Besong G, Battaglia G, D'Onofrio M, Di Marco R, Ngomba RT, Storto M, Castiglione M, Mangano K, Busceti CL, Nicoletti FR, Bacon K, Tusche M, Valenti O, Conn PJ, Bruno V, Nicoletti F. Besong G, et al. Among authors: mangano k. J Neurosci. 2002 Jul 1;22(13):5403-11. doi: 10.1523/JNEUROSCI.22-13-05403.2002. J Neurosci. 2002. PMID: 12097492 Free PMC article.
A potent immunomodulatory compound, (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid, prevents spontaneous and accelerated forms of autoimmune diabetes in NOD mice and inhibits the immunoinflammatory diabetes induced by multiple low doses of streptozotocin in CBA/H mice.
Stosic-Grujicic S, Cvetkovic I, Mangano K, Fresta M, Maksimovic-Ivanic D, Harhaji L, Popadic D, Momcilovic M, Miljkovic D, Kim J, Al-Abed Y, Nicoletti F. Stosic-Grujicic S, et al. Among authors: mangano k. J Pharmacol Exp Ther. 2007 Mar;320(3):1038-49. doi: 10.1124/jpet.106.109272. Epub 2006 Dec 5. J Pharmacol Exp Ther. 2007. PMID: 17148780
In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models.
Stojanovic I, Cuzzocrea S, Mangano K, Mazzon E, Miljkovic D, Wang M, Donia M, Al Abed Y, Kim J, Nicoletti F, Stosic-Grujicic S, Claesson M. Stojanovic I, et al. Among authors: mangano k. Clin Immunol. 2007 Jun;123(3):311-23. doi: 10.1016/j.clim.2007.03.004. Epub 2007 Apr 20. Clin Immunol. 2007. PMID: 17449326
163 results