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Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Blood. 2018 Aug 9;132(6):587-597. doi: 10.1182/blood-2018-03-840132. Epub 2018 Jun 8.
Blood. 2018.
PMID: 29884741
Free PMC article.
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.
Walker BA, Mavrommatis K, Wardell CP, Ashby TC, Bauer M, Davies F, Rosenthal A, Wang H, Qu P, Hoering A, Samur M, Towfic F, Ortiz M, Flynt E, Yu Z, Yang Z, Rozelle D, Obenauer J, Trotter M, Auclair D, Keats J, Bolli N, Fulciniti M, Szalat R, Moreau P, Durie B, Stewart AK, Goldschmidt H, Raab MS, Einsele H, Sonneveld P, San Miguel J, Lonial S, Jackson GH, Anderson KC, Avet-Loiseau H, Munshi N, Thakurta A, Morgan G.
Walker BA, et al. Among authors: ashby tc.
Leukemia. 2019 Jan;33(1):159-170. doi: 10.1038/s41375-018-0196-8. Epub 2018 Jul 2.
Leukemia. 2019.
PMID: 29967379
Free PMC article.
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Prognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems.
Guo W, Zhan Y, Mery D, Siegel ER, Sun F, Cheng Y, Ashby TC, Zhang Z, Bailey C, Alapat DV, Peng H, Hadidi SA, Thanendrarajan S, Schinke C, Zangari M, van Rhee F, Tricot G, Shaughnessy JD, Zhan F.
Guo W, et al. Among authors: ashby tc.
Blood Cancer J. 2024 Feb 14;14(1):30. doi: 10.1038/s41408-024-00998-9.
Blood Cancer J. 2024.
PMID: 38355688
Free PMC article.
No abstract available.
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AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity.
Bloedjes TA, de Wilde G, Khan GH, Ashby TC, Shaughnessy JD, Zhan F, Houtkooper RH, Bende RJ, van Noesel CJM, Spaargaren M, Guikema JEJ.
Bloedjes TA, et al. Among authors: ashby tc.
Blood Adv. 2023 May 9;7(9):1697-1712. doi: 10.1182/bloodadvances.2022007383.
Blood Adv. 2023.
PMID: 36322819
Free PMC article.
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A gene signature can predict risk of MGUS progressing to multiple myeloma.
Sun F, Cheng Y, Ying J, Mery D, Al Hadidi S, Wanchai V, Siegel ER, Xu H, Gai D, Ashby TC, Bailey C, Chen JR, Schinke C, Thanendrarajan S, Zangari M, Janz S, Barlogie B, Van Rhee F, Tricot G, Shaughnessy JD Jr, Zhan F.
Sun F, et al. Among authors: ashby tc.
J Hematol Oncol. 2023 Jun 29;16(1):70. doi: 10.1186/s13045-023-01472-y.
J Hematol Oncol. 2023.
PMID: 37386588
Free PMC article.
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TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies.
Li C, Xia J, Franqui-Machin R, Chen F, He Y, Ashby TC, Teng F, Xu H, Liu D, Gai D, Johnson SK, van Rhee F, Janz S, Shaughnessy JD Jr, Tricot G, Frech I, Zhan F.
Li C, et al. Among authors: ashby tc.
J Clin Invest. 2021 Jul 15;131(14):e146893. doi: 10.1172/JCI146893.
J Clin Invest. 2021.
PMID: 34061780
Free PMC article.
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Concomitant deletion of the short arm (del(1p13.3)) and amplification or gain (1q21) of chromosome 1 by fluorescence in situ hybridization are associated with a poor clinical outcome in multiple myeloma.
Mohan M, Gong Z, Ashby TC, Al Hadidi S, Thanendrarajan S, Schinke C, Alapat D, Shaughnessy JD Jr, Zhan F, van Rhee F, Sawyer JR, Tian E, Zangari M.
Mohan M, et al. Among authors: ashby tc.
Cancer. 2023 Aug 15;129(16):2491-2498. doi: 10.1002/cncr.34895. Epub 2023 Jun 6.
Cancer. 2023.
PMID: 37282609
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A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation.
Guo W, Strouse C, Mery D, Siegel ER, Munshi MN, Ashby TC, Cheng Y, Sun F, Wanchai V, Zhang Z, Bailey C, Alapat DV, Peng H, Al Hadidi S, Thanendrarajan S, Schinke C, Zangari M, van Rhee F, Tricot G, Shaughnessy JD Jr, Zhan F.
Guo W, et al. Among authors: ashby tc.
Cancers (Basel). 2024 Mar 11;16(6):1116. doi: 10.3390/cancers16061116.
Cancers (Basel). 2024.
PMID: 38539451
Free PMC article.
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