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Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.
Chahroudi A, Cartwright E, Lee ST, Mavigner M, Carnathan DG, Lawson B, Carnathan PM, Hashempoor T, Murphy MK, Meeker T, Ehnert S, Souder C, Else JG, Cohen J, Collman RG, Vanderford TH, Permar SR, Derdeyn CA, Villinger F, Silvestri G. Chahroudi A, et al. Among authors: permar sr. PLoS Pathog. 2014 Mar 6;10(3):e1003958. doi: 10.1371/journal.ppat.1003958. eCollection 2014 Mar. PLoS Pathog. 2014. PMID: 24604066 Free PMC article.
Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission.
Bialas KM, Tanaka T, Tran D, Varner V, Cisneros De La Rosa E, Chiuppesi F, Wussow F, Kattenhorn L, Macri S, Kunz EL, Estroff JA, Kirchherr J, Yue Y, Fan Q, Lauck M, O'Connor DH, Hall AH, Xavier A, Diamond DJ, Barry PA, Kaur A, Permar SR. Bialas KM, et al. Among authors: permar sr. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13645-50. doi: 10.1073/pnas.1511526112. Epub 2015 Oct 19. Proc Natl Acad Sci U S A. 2015. PMID: 26483473 Free PMC article.
Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.
Nelson CS, Cruz DV, Tran D, Bialas KM, Stamper L, Wu H, Gilbert M, Blair R, Alvarez X, Itell H, Chen M, Deshpande A, Chiuppesi F, Wussow F, Diamond DJ, Vandergrift N, Walter MR, Barry PA, Cohen-Wolkowiez M, Koelle K, Kaur A, Permar SR. Nelson CS, et al. Among authors: permar sr. JCI Insight. 2017 Jul 6;2(13):e94002. doi: 10.1172/jci.insight.94002. eCollection 2017 Jul 6. JCI Insight. 2017. PMID: 28679960 Free PMC article.
HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine.
McGuire EP, Fong Y, Toote C, Cunningham CK, McFarland EJ, Borkowsky W, Barnett S, Itell HL, Kumar A, Gray G, McElrath MJ, Tomaras GD, Permar SR, Fouda GG. McGuire EP, et al. Among authors: permar sr. J Virol. 2017 Dec 14;92(1):e01070-17. doi: 10.1128/JVI.01070-17. Print 2018 Jan 1. J Virol. 2017. PMID: 29021402 Free PMC article. Clinical Trial.
255 results