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The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation.
Cnop M, Hughes SJ, Igoillo-Esteve M, Hoppa MB, Sayyed F, van de Laar L, Gunter JH, de Koning EJ, Walls GV, Gray DW, Johnson PR, Hansen BC, Morris JF, Pipeleers-Marichal M, Cnop I, Clark A. Cnop M, et al. Among authors: de koning ej. Diabetologia. 2010 Feb;53(2):321-30. doi: 10.1007/s00125-009-1562-x. Epub 2009 Oct 24. Diabetologia. 2010. PMID: 19855953
Simultaneous pancreas-kidney transplantation in patients with type 1 diabetes reverses elevated MBL levels in association with MBL2 genotype and VEGF expression.
Bijkerk R, van der Pol P, Khairoun M, van Gijlswijk-Jansen DJ, Lievers E, de Vries AP, de Koning EJ, de Fijter HW, Roelen DL, Vossen RH, van Zonneveld AJ, van Kooten C, Reinders ME. Bijkerk R, et al. Among authors: de fijter hw, de vries ap, de koning ej. Diabetologia. 2016 Apr;59(4):853-8. doi: 10.1007/s00125-015-3858-3. Epub 2016 Jan 15. Diabetologia. 2016. PMID: 26768002 Free PMC article.
Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential.
Loomans CJM, Williams Giuliani N, Balak J, Ringnalda F, van Gurp L, Huch M, Boj SF, Sato T, Kester L, de Sousa Lopes SMC, Roost MS, Bonner-Weir S, Engelse MA, Rabelink TJ, Heimberg H, Vries RGJ, van Oudenaarden A, Carlotti F, Clevers H, de Koning EJP. Loomans CJM, et al. Stem Cell Reports. 2018 Mar 13;10(3):712-724. doi: 10.1016/j.stemcr.2018.02.005. Stem Cell Reports. 2018. PMID: 29539434 Free PMC article.
PRISM: A Novel Human Islet Isolation Technique.
Doppenberg JB, Engelse MA, de Koning EJP. Doppenberg JB, et al. Transplantation. 2022 Jun 1;106(6):1271-1278. doi: 10.1097/TP.0000000000003897. Epub 2022 Jul 22. Transplantation. 2022. PMID: 34342959
Chronic overproduction of islet amyloid polypeptide/amylin in transgenic mice: lysosomal localization of human islet amyloid polypeptide and lack of marked hyperglycaemia or hyperinsulinaemia.
Höppener JW, Verbeek JS, de Koning EJ, Oosterwijk C, van Hulst KL, Visser-Vernooy HJ, Hofhuis FM, van Gaalen S, Berends MJ, Hackeng WH, et al. Höppener JW, et al. Among authors: de koning ej. Diabetologia. 1993 Dec;36(12):1258-65. doi: 10.1007/BF00400803. Diabetologia. 1993. PMID: 8307253
272 results