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mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation.
Karonitsch T, Kandasamy RK, Kartnig F, Herdy B, Dalwigk K, Niederreiter B, Holinka J, Sevelda F, Windhager R, Bilban M, Weichhart T, Säemann M, Pap T, Steiner G, Smolen JS, Kiener HP, Superti-Furga G. Karonitsch T, et al. Among authors: pap t. Cell Rep. 2018 May 15;23(7):2157-2167. doi: 10.1016/j.celrep.2018.04.044. Cell Rep. 2018. PMID: 29768212 Free PMC article.
FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes.
Brandstetter B, Dalwigk K, Platzer A, Niederreiter B, Kartnig F, Fischer A, Vladimer GI, Byrne RA, Sevelda F, Holinka J, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T. Brandstetter B, et al. Among authors: pap t. Lab Invest. 2019 May;99(5):648-658. doi: 10.1038/s41374-018-0184-7. Epub 2019 Jan 24. Lab Invest. 2019. PMID: 30679758 Free article.
IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs.
Bonelli M, Dalwigk K, Platzer A, Olmos Calvo I, Hayer S, Niederreiter B, Holinka J, Sevelda F, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T. Bonelli M, et al. Among authors: pap t. Exp Mol Med. 2019 Jul 8;51(7):1-11. doi: 10.1038/s12276-019-0267-6. Exp Mol Med. 2019. PMID: 31285419 Free PMC article.
TNFR2 is critical for TNF-induced rheumatoid arthritis fibroblast-like synoviocyte inflammation.
Suto T, Tosevska A, Dalwigk K, Kugler M, Dellinger M, Stanic I, Platzer A, Niederreiter B, Sevelda F, Bonelli M, Pap T, Kiener H, Okamura K, Chikuda H, Aletaha D, Heinz LX, Karonitsch T. Suto T, et al. Among authors: pap t. Rheumatology (Oxford). 2022 Nov 2;61(11):4535-4546. doi: 10.1093/rheumatology/keac124. Rheumatology (Oxford). 2022. PMID: 35258553
Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis.
Korb-Pap A, Stratis A, Mühlenberg K, Niederreiter B, Hayer S, Echtermeyer F, Stange R, Zwerina J, Pap T, Pavenstädt H, Schett G, Smolen JS, Redlich K. Korb-Pap A, et al. Among authors: pap t. Ann Rheum Dis. 2012 Jun;71(6):1004-11. doi: 10.1136/annrheumdis-2011-200386. Epub 2012 Jan 18. Ann Rheum Dis. 2012. PMID: 22258493
TNF-induced structural joint damage is mediated by IL-1.
Zwerina J, Redlich K, Polzer K, Joosten L, Krönke G, Distler J, Hess A, Pundt N, Pap T, Hoffmann O, Gasser J, Scheinecker C, Smolen JS, van den Berg W, Schett G. Zwerina J, et al. Among authors: pap t. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11742-7. doi: 10.1073/pnas.0610812104. Epub 2007 Jul 3. Proc Natl Acad Sci U S A. 2007. PMID: 17609389 Free PMC article.
FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.
Wixler V, Cromme C, Retser E, Meyer LH, Smyth N, Mühlenberg K, Korb-Pap A, Koers-Wunrau C, Sotsios Y, Bassel-Duby R, Baeten D, Tak PP, Niederreiter B, Redlich K, Bertrand J, Skryabin BV, Ludwig S, Pap T. Wixler V, et al. Among authors: pap t. Ann Rheum Dis. 2015 Dec;74(12):2216-23. doi: 10.1136/annrheumdis-2013-205061. Epub 2014 Aug 14. Ann Rheum Dis. 2015. PMID: 25125695
Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis.
Beckmann D, Römer-Hillmann A, Krause A, Hansen U, Wehmeyer C, Intemann J, de Gorter DJJ, Dankbar B, Hillen J, Heitzmann M, Begemann I, Galic M, Weinhage T, Foell D, Ai R, Kremerskothen J, Kiener HP, Müller S, Kamradt T, Schröder C, Leitão E, Horsthemke B, Rosenstiel P, Nordström K, Gasparoni G, Gasparoni N, Walter J, Li N, Yang X, Chung HR, Pavenstädt H, Lindemann N, Schnittler HJ, Wang W, Firestein GS, Pap T, Korb-Pap A. Beckmann D, et al. Among authors: pap t. Nat Commun. 2021 Jun 15;12(1):3624. doi: 10.1038/s41467-021-23706-8. Nat Commun. 2021. PMID: 34131132 Free PMC article.
221 results