Macaulay VM - Search Results

1

Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.

Aleksic T, Gray N, Wu X, Rieunier G, Osher E, Mills J, Verrill C, Bryant RJ, Han C, Hutchinson K, Lambert AG, Kumar R, Hamdy FC, Weyer-Czernilofsky U, Sanderson MP, Bogenrieder T, Taylor S, Macaulay VM. Aleksic T, et al. Among authors: macaulay vm. Cancer Res. 2018 Jul 1;78(13):3497-3509. doi: 10.1158/0008-5472.CAN-17-3498. Epub 2018 May 7. Cancer Res. 2018. PMID: 29735545 Free PMC article.

2

Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells.

Macaulay VM, Everard MJ, Teale JD, Trott PA, Van Wyk JJ, Smith IE, Millar JL. Macaulay VM, et al. Cancer Res. 1990 Apr 15;50(8):2511-7. Cancer Res. 1990. PMID: 2156621

3

Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease.

Hellawell GO, Turner GD, Davies DR, Poulsom R, Brewster SF, Macaulay VM. Hellawell GO, et al. Among authors: macaulay vm. Cancer Res. 2002 May 15;62(10):2942-50. Cancer Res. 2002. PMID: 12019176

4

Silencing of the IGF1R gene enhances sensitivity to DNA-damaging agents in both PTEN wild-type and mutant human prostate cancer.

Rochester MA, Riedemann J, Hellawell GO, Brewster SF, Macaulay VM. Rochester MA, et al. Among authors: macaulay vm. Cancer Gene Ther. 2005 Jan;12(1):90-100. doi: 10.1038/sj.cgt.7700775. Cancer Gene Ther. 2005. PMID: 15499378

5

IGF1R signalling and its inhibition.

Riedemann J, Macaulay VM. Riedemann J, et al. Among authors: macaulay vm. Endocr Relat Cancer. 2006 Dec;13 Suppl 1:S33-43. doi: 10.1677/erc.1.01280. Endocr Relat Cancer. 2006. PMID: 17259557 Review.

6

The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma.

Yuen JS, Cockman ME, Sullivan M, Protheroe A, Turner GD, Roberts IS, Pugh CW, Werner H, Macaulay VM. Yuen JS, et al. Among authors: macaulay vm. Oncogene. 2007 Oct 4;26(45):6499-508. doi: 10.1038/sj.onc.1210474. Epub 2007 May 7. Oncogene. 2007. PMID: 17486080

7

The type 1 insulin-like growth factor receptor pathway.

Chitnis MM, Yuen JS, Protheroe AS, Pollak M, Macaulay VM. Chitnis MM, et al. Among authors: macaulay vm. Clin Cancer Res. 2008 Oct 15;14(20):6364-70. doi: 10.1158/1078-0432.CCR-07-4879. Clin Cancer Res. 2008. PMID: 18927274 Review.

8

Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells.

Aleksic T, Chitnis MM, Perestenko OV, Gao S, Thomas PH, Turner GD, Protheroe AS, Howarth M, Macaulay VM. Aleksic T, et al. Among authors: macaulay vm. Cancer Res. 2010 Aug 15;70(16):6412-9. doi: 10.1158/0008-5472.CAN-10-0052. Cancer Res. 2010. PMID: 20710042 Free PMC article.

9

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination.

Chitnis MM, Lodhia KA, Aleksic T, Gao S, Protheroe AS, Macaulay VM. Chitnis MM, et al. Among authors: macaulay vm. Oncogene. 2014 Nov 6;33(45):5262-73. doi: 10.1038/onc.2013.460. Epub 2013 Nov 4. Oncogene. 2014. PMID: 24186206 Free PMC article.

10

Can we unlock the potential of IGF-1R inhibition in cancer therapy?

King H, Aleksic T, Haluska P, Macaulay VM. King H, et al. Among authors: macaulay vm. Cancer Treat Rev. 2014 Oct;40(9):1096-105. doi: 10.1016/j.ctrv.2014.07.004. Epub 2014 Aug 4. Cancer Treat Rev. 2014. PMID: 25123819 Free PMC article. Review.

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