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Page 1
High Throughput Combinatorial Formatting of PcrV Nanobodies for Efficient Potency Improvement.
De Tavernier E, Detalle L, Morizzo E, Roobrouck A, De Taeye S, Rieger M, Verhaeghe T, Correia A, Van Hegelsom R, Figueirido R, Noens J, Steffensen S, Stöhr T, Van de Velde W, Depla E, Dombrecht B. De Tavernier E, et al. Among authors: detalle l. J Biol Chem. 2016 Jul 15;291(29):15243-55. doi: 10.1074/jbc.M115.684241. Epub 2016 May 20. J Biol Chem. 2016. PMID: 27226529 Free PMC article.
Nebulised ALX-0171 for respiratory syncytial virus lower respiratory tract infection in hospitalised children: a double-blind, randomised, placebo-controlled, phase 2b trial.
Cunningham S, Piedra PA, Martinon-Torres F, Szymanski H, Brackeva B, Dombrecht E, Detalle L, Fleurinck C; RESPIRE study group. Cunningham S, et al. Among authors: detalle l. Lancet Respir Med. 2021 Jan;9(1):21-32. doi: 10.1016/S2213-2600(20)30320-9. Epub 2020 Sep 28. Lancet Respir Med. 2021. PMID: 33002427 Clinical Trial.
Comparative Therapeutic Potential of ALX-0171 and Palivizumab against Respiratory Syncytial Virus Clinical Isolate Infection of Well-Differentiated Primary Pediatric Bronchial Epithelial Cell Cultures.
Broadbent L, Parke HG, Ferguson LJ, Millar A, Shields MD, Detalle L, Power UF. Broadbent L, et al. Among authors: detalle l. Antimicrob Agents Chemother. 2020 Jan 27;64(2):e02034-19. doi: 10.1128/AAC.02034-19. Print 2020 Jan 27. Antimicrob Agents Chemother. 2020. PMID: 31767728 Free PMC article.
Nanobodies® as inhaled biotherapeutics for lung diseases.
Van Heeke G, Allosery K, De Brabandere V, De Smedt T, Detalle L, de Fougerolles A. Van Heeke G, et al. Among authors: detalle l. Pharmacol Ther. 2017 Jan;169:47-56. doi: 10.1016/j.pharmthera.2016.06.012. Epub 2016 Jun 29. Pharmacol Ther. 2017. PMID: 27373507 Review.
Trivalency of a Nanobody Specific for the Human Respiratory Syncytial Virus Fusion Glycoprotein Drastically Enhances Virus Neutralization and Impacts Escape Mutant Selection.
Palomo C, Mas V, Detalle L, Depla E, Cano O, Vázquez M, Stortelers C, Melero JA. Palomo C, et al. Among authors: detalle l. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6498-6509. doi: 10.1128/AAC.00842-16. Print 2016 Nov. Antimicrob Agents Chemother. 2016. PMID: 27550346 Free PMC article.
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial.
De Leeuw E, Van Damme KFA, Declercq J, Bosteels C, Maes B, Tavernier SJ, Detalle L, Smart T, Glatt S, Debeuf N, Deckers J, Lameire S, Vandecasteele SJ, De Neve N, Demedts IK, Govaerts E, Knoop C, Vanhove K, Moutschen M, Terryn W, Depuydt P, Van Braeckel E, Haerynck F, Hendrickx TCJ, Parrein V, Lalla M, Brittain C, Lambrecht BN. De Leeuw E, et al. Among authors: detalle l. Respir Res. 2022 Aug 9;23(1):202. doi: 10.1186/s12931-022-02126-2. Respir Res. 2022. PMID: 35945604 Free PMC article. Clinical Trial.
Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial.
Declercq J, Bosteels C, Van Damme K, De Leeuw E, Maes B, Vandecauter A, Vermeersch S, Delporte A, Demeyere B, Vuylsteke M, Lalla M, Smart T, Detalle L, Bouw R, Streffer J, Degeeter T, Vergotte M, Guisez T, Van Braeckel E, Van Der Straeten C, Lambrecht BN. Declercq J, et al. Among authors: detalle l. Trials. 2020 Nov 19;21(1):934. doi: 10.1186/s13063-020-04884-0. Trials. 2020. PMID: 33213529 Free PMC article. Clinical Trial.
17 results