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Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress.
Peng H, Yang J, Li G, You Q, Han W, Li T, Gao D, Xie X, Lee BH, Du J, Hou J, Zhang T, Rao H, Huang Y, Li Q, Zeng R, Hui L, Wang H, Xia Q, Zhang X, He Y, Komatsu M, Dikic I, Finley D, Hu R. Peng H, et al. Among authors: gao d. Cell Res. 2017 May;27(5):657-674. doi: 10.1038/cr.2017.40. Epub 2017 Mar 21. Cell Res. 2017. PMID: 28322253 Free PMC article.
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.
Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, Liu Y, Xie A, Kuai X, Chirn GW, Zhou H, Zeng R, Hu R, Qin J, Meng FL, Wei W, Ji H, Gao D. Xie X, et al. Among authors: gao d. Nat Cell Biol. 2018 Mar;20(3):320-331. doi: 10.1038/s41556-017-0033-8. Epub 2018 Feb 5. Nat Cell Biol. 2018. PMID: 29403037 Free PMC article.
Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin β1.
Zhao G, Gong L, Su D, Jin Y, Guo C, Yue M, Yao S, Qin Z, Ye Y, Tang Y, Wu Q, Zhang J, Cui B, Ding Q, Huang H, Hu L, Chen Y, Zhang P, Hu G, Chen L, Wong KK, Gao D, Ji H. Zhao G, et al. Among authors: gao d. J Clin Invest. 2019 Mar 1;129(3):972-987. doi: 10.1172/JCI122779. Epub 2019 Jan 28. J Clin Invest. 2019. PMID: 30688657 Free PMC article.
TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM.
Wang K, Fang S, Liu Q, Gao J, Wang X, Zhu H, Zhu Z, Ji F, Wu J, Ma Y, Hu L, Shen X, Gao D, Zhu J, Liu P, Zhou H. Wang K, et al. Among authors: gao d, gao j. EBioMedicine. 2019 Apr;42:458-469. doi: 10.1016/j.ebiom.2019.03.058. Epub 2019 Mar 27. EBioMedicine. 2019. PMID: 30926424 Free PMC article.
5,209 results