Gryboś A - Search Results

1

Design, synthesis and cardiovascular evaluation of some aminoisopropanoloxy derivatives of xanthone.

Kubacka M, Szkaradek N, Mogilski S, Pańczyk K, Siwek A, Gryboś A, Filipek B, Żmudzki P, Marona H, Waszkielewicz AM. Kubacka M, et al. Among authors: grybos a. Bioorg Med Chem. 2018 Jul 30;26(13):3773-3784. doi: 10.1016/j.bmc.2018.04.038. Epub 2018 Apr 18. Bioorg Med Chem. 2018. PMID: 29706529

2

Design, synthesis, and anticonvulsant activity of some derivatives of xanthone with aminoalkanol moieties.

Waszkielewicz AM, Słoczyńska K, Pękala E, Żmudzki P, Siwek A, Gryboś A, Marona H. Waszkielewicz AM, et al. Among authors: grybos a. Chem Biol Drug Des. 2017 Mar;89(3):339-352. doi: 10.1111/cbdd.12842. Epub 2016 Sep 28. Chem Biol Drug Des. 2017. PMID: 27543433

3

Synthesis and activity of newly designed aroxyalkyl or aroxyethoxyethyl derivatives of piperazine on the cardiovascular and the central nervous systems.

Waszkielewicz AM, Kubacka M, Pańczyk K, Mogilski S, Siwek A, Głuch-Lutwin M, Gryboś A, Filipek B. Waszkielewicz AM, et al. Among authors: grybos a. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5315-5321. doi: 10.1016/j.bmcl.2016.09.037. Epub 2016 Sep 15. Bioorg Med Chem Lett. 2016. PMID: 27692547

4

Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system.

Pańczyk K, Pytka K, Jakubczyk M, Rapacz A, Sałat K, Furgała A, Siwek A, Głuch-Lutwin M, Gryboś A, Słoczyńska K, Pękala E, Żmudzki P, Bucki A, Kołaczkowski M, Żelaszczyk D, Marona H, Waszkielewicz AM. Pańczyk K, et al. Among authors: grybos a. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2039-2049. doi: 10.1016/j.bmcl.2018.04.059. Epub 2018 Apr 25. Bioorg Med Chem Lett. 2018. PMID: 29730027

5

Structure-5-HT/D₂ Receptor Affinity Relationship in a New Group of 1-Arylpiperazynylalkyl Derivatives of 8-Dialkylamino-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione.

Żmudzki P, Satała G, Chłoń-Rzepa G, Bojarski AJ, Kazek G, Siwek A, Gryboś A, Głuch-Lutwin M, Wesołowska A, Pawłowski M. Żmudzki P, et al. Among authors: grybos a. Arch Pharm (Weinheim). 2016 Oct;349(10):774-784. doi: 10.1002/ardp.201600162. Epub 2016 Aug 11. Arch Pharm (Weinheim). 2016. PMID: 27510801

6

Synthesis of a new series of aryl/heteroarylpiperazinyl derivatives of 8-acetyl-7-hydroxy-4-methylcoumarin with low nanomolar 5-HT_1A affinities.

Ostrowska K, Młodzikowska K, Głuch-Lutwin M, Gryboś A, Siwek A. Ostrowska K, et al. Among authors: grybos a. Eur J Med Chem. 2017 Sep 8;137:108-116. doi: 10.1016/j.ejmech.2017.05.047. Epub 2017 May 26. Eur J Med Chem. 2017. PMID: 28575721

7

5-HT_1A and 5-HT_2A receptors affinity, docking studies and pharmacological evaluation of a series of 8-acetyl-7-hydroxy-4-methylcoumarin derivatives.

Ostrowska K, Grzeszczuk D, Głuch-Lutwin M, Gryboś A, Siwek A, Leśniak A, Sacharczuk M, Trzaskowski B. Ostrowska K, et al. Among authors: grybos a. Bioorg Med Chem. 2018 Jan 15;26(2):527-535. doi: 10.1016/j.bmc.2017.12.016. Epub 2017 Dec 9. Bioorg Med Chem. 2018. PMID: 29269256

8

Antiallodynic and antihyperalgesic activity of new 3,3-diphenyl-propionamides with anticonvulsant activity in models of pain in mice.

Rapacz A, Obniska J, Koczurkiewicz P, Wójcik-Pszczoła K, Siwek A, Gryboś A, Rybka S, Karcz A, Pękala E, Filipek B. Rapacz A, et al. Among authors: grybos a. Eur J Pharmacol. 2018 Feb 15;821:39-48. doi: 10.1016/j.ejphar.2017.12.036. Epub 2017 Dec 17. Eur J Pharmacol. 2018. PMID: 29262297

9

Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.

Bucki A, Marcinkowska M, Śniecikowska J, Więckowski K, Pawłowski M, Głuch-Lutwin M, Gryboś A, Siwek A, Pytka K, Jastrzębska-Więsek M, Partyka A, Wesołowska A, Mierzejewski P, Kołaczkowski M. Bucki A, et al. Among authors: grybos a. J Med Chem. 2017 Sep 14;60(17):7483-7501. doi: 10.1021/acs.jmedchem.7b00839. Epub 2017 Aug 18. J Med Chem. 2017. PMID: 28763213

10

Development of selective agents targeting serotonin 5HT_1A receptors with subnanomolar activities based on a coumarin core.

Ostrowska K, Grzeszczuk D, Głuch-Lutwin M, Gryboś A, Siwek A, Dobrzycki Ł, Trzaskowski B. Ostrowska K, et al. Among authors: grybos a. Medchemcomm. 2017 Jul 3;8(8):1690-1696. doi: 10.1039/c7md00281e. eCollection 2017 Aug 1. Medchemcomm. 2017. PMID: 30108880 Free PMC article.

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