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Overexpression of CYB5R3 and NQO1, two NAD+ -producing enzymes, mimics aspects of caloric restriction.
Diaz-Ruiz A, Lanasa M, Garcia J, Mora H, Fan F, Martin-Montalvo A, Di Francesco A, Calvo-Rubio M, Salvador-Pascual A, Aon MA, Fishbein KW, Pearson KJ, Villalba JM, Navas P, Bernier M, de Cabo R. Diaz-Ruiz A, et al. Among authors: salvador pascual a. Aging Cell. 2018 Aug;17(4):e12767. doi: 10.1111/acel.12767. Epub 2018 Apr 28. Aging Cell. 2018. PMID: 29706024 Free PMC article.
G6PD protects from oxidative damage and improves healthspan in mice.
Nóbrega-Pereira S, Fernandez-Marcos PJ, Brioche T, Gomez-Cabrera MC, Salvador-Pascual A, Flores JM, Viña J, Serrano M. Nóbrega-Pereira S, et al. Nat Commun. 2016 Mar 15;7:10894. doi: 10.1038/ncomms10894. Nat Commun. 2016. PMID: 26976705 Free PMC article.
Glucose 6-P dehydrogenase delays the onset of frailty by protecting against muscle damage.
Arc-Chagnaud C, Salvador-Pascual A, Garcia-Dominguez E, Olaso-Gonzalez G, Correas AG, Serna E, Brioche T, Chopard A, Fernandez-Marcos PJ, Serrano M, Serrano AL, Muñoz-Cánoves P, Sebastiá V, Viña J, Gomez-Cabrera MC. Arc-Chagnaud C, et al. Among authors: salvador pascual a. J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1879-1896. doi: 10.1002/jcsm.12792. Epub 2021 Oct 26. J Cachexia Sarcopenia Muscle. 2021. PMID: 34704386 Free PMC article.
Redox modulation of muscle mass and function.
Gomez-Cabrera MC, Arc-Chagnaud C, Salvador-Pascual A, Brioche T, Chopard A, Olaso-Gonzalez G, Viña J. Gomez-Cabrera MC, et al. Among authors: salvador pascual a. Redox Biol. 2020 Aug;35:101531. doi: 10.1016/j.redox.2020.101531. Epub 2020 Apr 18. Redox Biol. 2020. PMID: 32371010 Free PMC article. Review.
Exercise training as a drug to treat age associated frailty.
Viña J, Salvador-Pascual A, Tarazona-Santabalbina FJ, Rodriguez-Mañas L, Gomez-Cabrera MC. Viña J, et al. Free Radic Biol Med. 2016 Sep;98:159-164. doi: 10.1016/j.freeradbiomed.2016.03.024. Epub 2016 Mar 25. Free Radic Biol Med. 2016. PMID: 27021963 Review.
Sarcopenia, frailty and their prevention by exercise.
Nascimento CM, Ingles M, Salvador-Pascual A, Cominetti MR, Gomez-Cabrera MC, Viña J. Nascimento CM, et al. Among authors: salvador pascual a. Free Radic Biol Med. 2019 Feb 20;132:42-49. doi: 10.1016/j.freeradbiomed.2018.08.035. Epub 2018 Aug 31. Free Radic Biol Med. 2019. PMID: 30176345 Review.
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