Horwood NJ - Search Results

1

Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to G_Alert.

Lee G, Espirito Santo AI, Zwingenberger S, Cai L, Vogl T, Feldmann M, Horwood NJ, Chan JK, Nanchahal J. Lee G, et al. Among authors: horwood nj. Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4463-E4472. doi: 10.1073/pnas.1802893115. Epub 2018 Apr 19. Proc Natl Acad Sci U S A. 2018. PMID: 29674451 Free PMC article.

2

High-efficiency gene transfer into nontransformed cells: utility for studying gene regulation and analysis of potential therapeutic targets.

Horwood NJ, Smith C, Andreakos E, Quattrocchi E, Brennan FM, Feldmann M, Foxwell BM. Horwood NJ, et al. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S215-25. doi: 10.1186/ar560. Epub 2002 May 9. Arthritis Res. 2002. PMID: 12110141 Free PMC article. Review.

3

A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis.

Campbell J, Ciesielski CJ, Hunt AE, Horwood NJ, Beech JT, Hayes LA, Denys A, Feldmann M, Brennan FM, Foxwell BM. Campbell J, et al. Among authors: horwood nj. J Immunol. 2004 Dec 1;173(11):6928-37. doi: 10.4049/jimmunol.173.11.6928. J Immunol. 2004. PMID: 15557189

4

IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages.

Smallie T, Ricchetti G, Horwood NJ, Feldmann M, Clark AR, Williams LM. Smallie T, et al. Among authors: horwood nj. J Exp Med. 2010 Sep 27;207(10):2081-8. doi: 10.1084/jem.20100414. Epub 2010 Aug 30. J Exp Med. 2010. PMID: 20805562 Free PMC article.

5

TNF-alpha promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells.

Glass GE, Chan JK, Freidin A, Feldmann M, Horwood NJ, Nanchahal J. Glass GE, et al. Among authors: horwood nj. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1585-90. doi: 10.1073/pnas.1018501108. Epub 2011 Jan 5. Proc Natl Acad Sci U S A. 2011. PMID: 21209334 Free PMC article.

6

Alarmins: awaiting a clinical response.

Chan JK, Roth J, Oppenheim JJ, Tracey KJ, Vogl T, Feldmann M, Horwood N, Nanchahal J. Chan JK, et al. J Clin Invest. 2012 Aug;122(8):2711-9. doi: 10.1172/JCI62423. Epub 2012 Aug 1. J Clin Invest. 2012. PMID: 22850880 Free PMC article. Review.

7

OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis.

Gwyer Findlay E, Danks L, Madden J, Cavanagh MM, McNamee K, McCann F, Snelgrove RJ, Shaw S, Feldmann M, Taylor PC, Horwood NJ, Hussell T. Gwyer Findlay E, et al. Among authors: horwood nj. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2289-94. doi: 10.1073/pnas.1321071111. Epub 2014 Jan 27. Proc Natl Acad Sci U S A. 2014. PMID: 24469824 Free PMC article.

8

Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response.

Chan JK, Glass GE, Ersek A, Freidin A, Williams GA, Gowers K, Espirito Santo AI, Jeffery R, Otto WR, Poulsom R, Feldmann M, Rankin SM, Horwood NJ, Nanchahal J. Chan JK, et al. Among authors: horwood nj. EMBO Mol Med. 2015 May;7(5):547-61. doi: 10.15252/emmm.201404487. EMBO Mol Med. 2015. PMID: 25770819 Free PMC article.

9

Selective inhibition of TNFR1 reduces osteoclast numbers and is differentiated from anti-TNF in a LPS-driven model of inflammatory bone loss.

Espirito Santo AI, Ersek A, Freidin A, Feldmann M, Stoop AA, Horwood NJ. Espirito Santo AI, et al. Among authors: horwood nj. Biochem Biophys Res Commun. 2015 Sep 4;464(4):1145-1150. doi: 10.1016/j.bbrc.2015.07.094. Epub 2015 Jul 22. Biochem Biophys Res Commun. 2015. PMID: 26208457

10

Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment.

Page TH, Urbaniak AM, Espirito Santo AI, Danks L, Smallie T, Williams LM, Horwood NJ. Page TH, et al. Among authors: horwood nj. Biochem Biophys Res Commun. 2018 May 5;499(2):260-266. doi: 10.1016/j.bbrc.2018.03.140. Epub 2018 Mar 22. Biochem Biophys Res Commun. 2018. PMID: 29567473 Free PMC article.

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