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Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression.
Lanuza PM, Vigueras A, Olivan S, Prats AC, Costas S, Llamazares G, Sanchez-Martinez D, Ayuso JM, Fernandez L, Ochoa I, Pardo J. Lanuza PM, et al. Among authors: pardo j. Oncoimmunology. 2018 Feb 12;7(4):e1395123. doi: 10.1080/2162402X.2017.1395123. eCollection 2018. Oncoimmunology. 2018. PMID: 29632716 Free PMC article.
All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity.
Sanchez-Martínez D, Krzywinska E, Rathore MG, Saumet A, Cornillon A, Lopez-Royuela N, Martínez-Lostao L, Ramirez-Labrada A, Lu ZY, Rossi JF, Fernández-Orth D, Escorza S, Anel A, Lecellier CH, Pardo J, Villalba M. Sanchez-Martínez D, et al. Among authors: pardo j. Int J Biochem Cell Biol. 2014 Apr;49:42-52. doi: 10.1016/j.biocel.2014.01.003. Epub 2014 Jan 15. Int J Biochem Cell Biol. 2014. PMID: 24440757
Human NK cells activated by EBV+ lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.
Sánchez-Martínez D, Azaceta G, Muntasell A, Aguiló N, Núñez D, Gálvez EM, Naval J, Anel A, Palomera L, Vilches C, Marzo I, Villalba M, Pardo J. Sánchez-Martínez D, et al. Among authors: pardo j. Oncoimmunology. 2015 Jan 9;4(3):e991613. doi: 10.4161/2162402X.2014.991613. eCollection 2015 Mar. Oncoimmunology. 2015. PMID: 25949911 Free PMC article.
How Do Cytotoxic Lymphocytes Kill Cancer Cells?
Martínez-Lostao L, Anel A, Pardo J. Martínez-Lostao L, et al. Among authors: pardo j. Clin Cancer Res. 2015 Nov 15;21(22):5047-56. doi: 10.1158/1078-0432.CCR-15-0685. Clin Cancer Res. 2015. PMID: 26567364 Review.
Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells.
Sánchez-Martínez D, Lanuza PM, Gómez N, Muntasell A, Cisneros E, Moraru M, Azaceta G, Anel A, Martínez-Lostao L, Villalba M, Palomera L, Vilches C, García Marco JA, Pardo J. Sánchez-Martínez D, et al. Among authors: pardo j. Front Immunol. 2016 Oct 27;7:454. doi: 10.3389/fimmu.2016.00454. eCollection 2016. Front Immunol. 2016. PMID: 27833611 Free PMC article.
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors.
Sanchez-Martinez D, Allende-Vega N, Orecchioni S, Talarico G, Cornillon A, Vo DN, Rene C, Lu ZY, Krzywinska E, Anel A, Galvez EM, Pardo J, Robert B, Martineau P, Hicheri Y, Bertolini F, Cartron G, Villalba M. Sanchez-Martinez D, et al. Among authors: pardo j. Theranostics. 2018 Jun 14;8(14):3856-3869. doi: 10.7150/thno.25149. eCollection 2018. Theranostics. 2018. PMID: 30083264 Free PMC article.
Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
Santiago L, Castro M, Sanz-Pamplona R, Garzón M, Ramirez-Labrada A, Tapia E, Moreno V, Layunta E, Gil-Gómez G, Garrido M, Peña R, Lanuza PM, Comas L, Jaime-Sanchez P, Uranga-Murillo I, Del Campo R, Pelegrín P, Camerer E, Martínez-Lostao L, Muñoz G, Uranga JA, Alcalde A, Galvez EM, Ferrandez A, Bird PI, Metkar S, Arias MA, Pardo J. Santiago L, et al. Among authors: pardo j. Cell Rep. 2020 Jul 7;32(1):107847. doi: 10.1016/j.celrep.2020.107847. Cell Rep. 2020. PMID: 32640217 Free article.
1,046 results