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Functional Precision Medicine Identifies Novel Druggable Targets and Therapeutic Options in Head and Neck Cancer.
Xu C, Nikolova O, Basom RS, Mitchell RM, Shaw R, Moser RD, Park H, Gurley KE, Kao MC, Green CL, Schaub FX, Diaz RL, Swan HA, Jang IS, Guinney J, Gadi VK, Margolin AA, Grandori C, Kemp CJ, Méndez E. Xu C, et al. Among authors: schaub fx. Clin Cancer Res. 2018 Jun 15;24(12):2828-2843. doi: 10.1158/1078-0432.CCR-17-1339. Epub 2018 Mar 29. Clin Cancer Res. 2018. PMID: 29599409 Free PMC article.
Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state.
Rounbehler RJ, Fallahi M, Yang C, Steeves MA, Li W, Doherty JR, Schaub FX, Sanduja S, Dixon DA, Blackshear PJ, Cleveland JL. Rounbehler RJ, et al. Among authors: schaub fx. Cell. 2012 Aug 3;150(3):563-74. doi: 10.1016/j.cell.2012.06.033. Cell. 2012. PMID: 22863009 Free PMC article.
TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia.
Yun S, Vincelette ND, Yu X, Watson GW, Fernandez MR, Yang C, Hitosugi T, Cheng CH, Freischel AR, Zhang L, Li W, Hou H, Schaub FX, Vedder AR, Cen L, McGraw KL, Moon J, Murphy DJ, Ballabio A, Kaufmann SH, Berglund AE, Cleveland JL. Yun S, et al. Among authors: schaub fx. Blood Cancer Discov. 2021 Mar;2(2):162-185. doi: 10.1158/2643-3230.BCD-20-0029. Blood Cancer Discov. 2021. PMID: 33860275 Free PMC article.
Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma.
Hoellein A, Fallahi M, Schoeffmann S, Steidle S, Schaub FX, Rudelius M, Laitinen I, Nilsson L, Goga A, Peschel C, Nilsson JA, Cleveland JL, Keller U. Hoellein A, et al. Among authors: schaub fx. Blood. 2014 Sep 25;124(13):2081-90. doi: 10.1182/blood-2014-06-584524. Epub 2014 Aug 20. Blood. 2014. PMID: 25143484 Free PMC article.
CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.
Amelio AL, Fallahi M, Schaub FX, Zhang M, Lawani MB, Alperstein AS, Southern MR, Young BM, Wu L, Zajac-Kaye M, Kaye FJ, Cleveland JL, Conkright MD. Amelio AL, et al. Among authors: schaub fx. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3260-8. doi: 10.1073/pnas.1319176111. Epub 2014 Jul 28. Proc Natl Acad Sci U S A. 2014. PMID: 25071166 Free PMC article.
17 results