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Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell-Derived RPE and Photoreceptor Cells.
Gonzalez-Cordero A, Goh D, Kruczek K, Naeem A, Fernando M, Kleine Holthaus SM, Takaaki M, Blackford SJI, Kloc M, Agundez L, Sampson RD, Borooah S, Ovando-Roche P, Mehat MS, West EL, Smith AJ, Pearson RA, Ali RR. Gonzalez-Cordero A, et al. Among authors: ali rr. Hum Gene Ther. 2018 Oct;29(10):1124-1139. doi: 10.1089/hum.2018.027. Epub 2018 May 14. Hum Gene Ther. 2018. PMID: 29580100
Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis.
Broderick CA, Smith AJ, Balaggan KS, Georgiadis A, Buch PK, Trittibach PC, Barker SE, Sarra GM, Thrasher AJ, Dick AD, Ali RR. Broderick CA, et al. Among authors: ali rr. Mol Ther. 2005 Aug;12(2):369-73. doi: 10.1016/j.ymthe.2005.03.018. Mol Ther. 2005. PMID: 16043105 Free article.
Absence of chx10 causes neural progenitors to persist in the adult retina.
Dhomen NS, Balaggan KS, Pearson RA, Bainbridge JW, Levine EM, Ali RR, Sowden JC. Dhomen NS, et al. Among authors: ali rr. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):386-96. doi: 10.1167/iovs.05-0428. Invest Ophthalmol Vis Sci. 2006. PMID: 16384989 Free PMC article.
Effective gene therapy with nonintegrating lentiviral vectors.
Yáñez-Muñoz RJ, Balaggan KS, MacNeil A, Howe SJ, Schmidt M, Smith AJ, Buch P, MacLaren RE, Anderson PN, Barker SE, Duran Y, Bartholomae C, von Kalle C, Heckenlively JR, Kinnon C, Ali RR, Thrasher AJ. Yáñez-Muñoz RJ, et al. Among authors: ali rr. Nat Med. 2006 Mar;12(3):348-53. doi: 10.1038/nm1365. Epub 2006 Feb 19. Nat Med. 2006. PMID: 16491086
Gene therapeutic prospects in early onset of severe retinal dystrophy: restoration of vision in RPE65 Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium.
Rolling F, Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Rolling F, et al. Among authors: ali rr. Bull Mem Acad R Med Belg. 2006;161(10-12):497-508; discussion 508-9. Bull Mem Acad R Med Belg. 2006. PMID: 17503728
255 results