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Ion channels as therapeutic targets: a drug discovery perspective.
Bagal SK, Brown AD, Cox PJ, Omoto K, Owen RM, Pryde DC, Sidders B, Skerratt SE, Stevens EB, Storer RI, Swain NA. Bagal SK, et al. Among authors: pryde dc. J Med Chem. 2013 Feb 14;56(3):593-624. doi: 10.1021/jm3011433. Epub 2012 Nov 29. J Med Chem. 2013. PMID: 23121096 Review.
Corrigendum to "Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K2P18.1" [Bioorg. Med. Chem. Lett. 26 (2016) 4919-4924].
Monteillier A, Loucif A, Omoto K, Stevens EB, Lainez S, Saintot PP, Cao L, Pryde DC. Monteillier A, et al. Among authors: pryde dc. Bioorg Med Chem Lett. 2017 May 1;27(9):2082. doi: 10.1016/j.bmcl.2017.02.063. Epub 2017 Mar 17. Bioorg Med Chem Lett. 2017. PMID: 28320618 No abstract available.
Valproic acid interactions with the NavMs voltage-gated sodium channel.
Zanatta G, Sula A, Miles AJ, Ng LCT, Torella R, Pryde DC, DeCaen PG, Wallace BA. Zanatta G, et al. Among authors: pryde dc. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26549-26554. doi: 10.1073/pnas.1909696116. Epub 2019 Dec 10. Proc Natl Acad Sci U S A. 2019. PMID: 31822620 Free PMC article.
Exploring the Dynamics of the TWIK-1 Channel.
Oakes V, Furini S, Pryde D, Domene C. Oakes V, et al. Biophys J. 2016 Aug 23;111(4):775-784. doi: 10.1016/j.bpj.2016.07.009. Biophys J. 2016. PMID: 27558721 Free PMC article.
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.
Schewe M, Sun H, Mert Ü, Mackenzie A, Pike ACW, Schulz F, Constantin C, Vowinkel KS, Conrad LJ, Kiper AK, Gonzalez W, Musinszki M, Tegtmeier M, Pryde DC, Belabed H, Nazare M, de Groot BL, Decher N, Fakler B, Carpenter EP, Tucker SJ, Baukrowitz T. Schewe M, et al. Among authors: pryde dc. Science. 2019 Feb 22;363(6429):875-880. doi: 10.1126/science.aav0569. Science. 2019. PMID: 30792303 Free PMC article.
55 results