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Domain order of a bispecific diabody dramatically enhances its antitumor activity beyond structural format conversion: the case of the hEx3 diabody.
Asano R, Kumagai T, Nagai K, Taki S, Shimomura I, Arai K, Ogata H, Okada M, Hayasaka F, Sanada H, Nakanishi T, Karvonen T, Hayashi H, Katayose Y, Unno M, Kudo T, Umetsu M, Kumagai I. Asano R, et al. Among authors: nagai k. Protein Eng Des Sel. 2013 May;26(5):359-67. doi: 10.1093/protein/gzt009. Epub 2013 Mar 6. Protein Eng Des Sel. 2013. PMID: 23468569
Structural and functional characterization of nylon hydrolases.
Negoro S, Kato DI, Ohki T, Yasuhira K, Kawashima Y, Nagai K, Takeo M, Shibata N, Kamiya K, Shigeta Y. Negoro S, et al. Among authors: nagai k. Methods Enzymol. 2021;648:357-389. doi: 10.1016/bs.mie.2020.11.004. Epub 2020 Dec 29. Methods Enzymol. 2021. PMID: 33579412
Crystallization and X-ray diffraction analysis of nylon-oligomer hydrolase (NylC) from Agromyces sp. KY5R.
Yasuhira K, Shibata N, Tanaka Y, Kumagai N, Tanaka Y, Nagai K, Kato D, Takeo M, Negoro S, Higuchi Y. Yasuhira K, et al. Among authors: nagai k. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):892-5. doi: 10.1107/S1744309111022858. Epub 2011 Jul 19. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21821888 Free PMC article.
Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis.
Negoro S, Shibata N, Tanaka Y, Yasuhira K, Shibata H, Hashimoto H, Lee YH, Oshima S, Santa R, Oshima S, Mochiji K, Goto Y, Ikegami T, Nagai K, Kato D, Takeo M, Higuchi Y. Negoro S, et al. Among authors: nagai k. J Biol Chem. 2012 Feb 10;287(7):5079-90. doi: 10.1074/jbc.M111.321992. Epub 2011 Dec 19. J Biol Chem. 2012. PMID: 22187439 Free PMC article.
SKIP modifies gene expression by affecting both transcription and splicing.
Nagai K, Yamaguchi T, Takami T, Kawasumi A, Aizawa M, Masuda N, Shimizu M, Tominaga S, Ito T, Tsukamoto T, Osumi T. Nagai K, et al. Biochem Biophys Res Commun. 2004 Apr 2;316(2):512-7. doi: 10.1016/j.bbrc.2004.02.077. Biochem Biophys Res Commun. 2004. PMID: 15020246
3,817 results