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Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.
O'Dowd CR, Helm MD, Rountree JSS, Flasz JT, Arkoudis E, Miel H, Hewitt PR, Jordan L, Barker O, Hughes C, Rozycka E, Cassidy E, McClelland K, Odrzywol E, Page N, Feutren-Burton S, Dvorkin S, Gavory G, Harrison T. O'Dowd CR, et al. Among authors: hughes c. ACS Med Chem Lett. 2018 Feb 21;9(3):238-243. doi: 10.1021/acsmedchemlett.7b00512. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541367 Free PMC article.
Biochemical characterization of the Eya and PP2A-B55α interaction.
Alderman C, Anderson R, Zhang L, Hughes CJ, Li X, Ebmeier C, Wagley ME, Ahn NG, Ford HL, Zhao R. Alderman C, et al. Among authors: hughes cj. J Biol Chem. 2024 May 23:107408. doi: 10.1016/j.jbc.2024.107408. Online ahead of print. J Biol Chem. 2024. PMID: 38796066 Free article.
Notes from the Field: Clade II Mpox Surveillance Update - United States, October 2023-April 2024.
Tuttle A, Hughes CM, Dvorak M, Aeschleman L, Davidson W, Wilkins K, Gigante C, Satheshkumar PS, Rao AK, Minhaj FS, Christensen BE, McQuiston JH, Hutson CL, McCollum AM. Tuttle A, et al. Among authors: hughes cm. MMWR Morb Mortal Wkly Rep. 2024 May 23;73(20):474-476. doi: 10.15585/mmwr.mm7320a4. MMWR Morb Mortal Wkly Rep. 2024. PMID: 38781102 Free PMC article. No abstract available.
Locus coeruleus integrity is related to an exploitation-based decision-making bias in older adulthood.
Turner GR, Hewan P, Wearn A, van Dooren R, Wyatt L, Leppert IR, Baracchini G, Hughes C, Williams KM, Sylvain E, Tremblay-Mercier J, Poirier J, Villeneuve S, Tardif C, Spreng RN; PREVENT-AD Research Group. Turner GR, et al. Among authors: hughes c. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2322617121. doi: 10.1073/pnas.2322617121. Epub 2024 May 21. Proc Natl Acad Sci U S A. 2024. PMID: 38771873 Free article.
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial.
Parker CC, Clarke NW, Cook AD, Kynaston H, Catton CN, Cross WR, Petersen PM, Persad RA, Saad F, Bower LC, Logue J, Payne H, Forcat S, Goldstein C, Murphy C, Anderson J, Barkati M, Bottomley DM, Branagan J, Choudhury A, Chung PWM, Cogley L, Goh CL, Hoskin P, Khoo V, Malone SC, Masters L, Morris SL, Nabid A, Ong AD, Raman R, Tarver KL, Tree AC, Worlding J, Wylie JP, Zarkar AM, Parulekar WR, Parmar MKB, Sydes MR; RADICALS investigators. Parker CC, et al. Lancet. 2024 May 16:S0140-6736(24)00548-8. doi: 10.1016/S0140-6736(24)00548-8. Online ahead of print. Lancet. 2024. PMID: 38763154 Free article.
3,824 results