Meijer L - Search Results

1

Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.

Billot K, Coquil C, Villiers B, Josselin-Foll B, Desban N, Delehouzé C, Oumata N, Le Meur Y, Boletta A, Weimbs T, Grosch M, Witzgall R, Saunier S, Fischer E, Pontoglio M, Fautrel A, Mrug M, Wallace D, Tran PV, Trudel M, Bukanov N, Ibraghimov-Beskrovnaya O, Meijer L. Billot K, et al. Among authors: meijer l. Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F57-F73. doi: 10.1152/ajprenal.00489.2017. Epub 2018 Mar 14. Am J Physiol Renal Physiol. 2018. PMID: 29537311 Free PMC article.

2

Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials.

Meijer L, Raymond E. Meijer L, et al. Acc Chem Res. 2003 Jun;36(6):417-25. doi: 10.1021/ar0201198. Acc Chem Res. 2003. PMID: 12809528 Review.

3

Roscovitine targets, protein kinases and pyridoxal kinase.

Bach S, Knockaert M, Reinhardt J, Lozach O, Schmitt S, Baratte B, Koken M, Coburn SP, Tang L, Jiang T, Liang DC, Galons H, Dierick JF, Pinna LA, Meggio F, Totzke F, Schächtele C, Lerman AS, Carnero A, Wan Y, Gray N, Meijer L. Bach S, et al. Among authors: meijer l. J Biol Chem. 2005 Sep 2;280(35):31208-19. doi: 10.1074/jbc.M500806200. Epub 2005 Jun 23. J Biol Chem. 2005. PMID: 15975926 Free article.

4

CDK/GSK-3 inhibitors as therapeutic agents for parenchymal renal diseases.

Obligado SH, Ibraghimov-Beskrovnaya O, Zuk A, Meijer L, Nelson PJ. Obligado SH, et al. Among authors: meijer l. Kidney Int. 2008 Mar;73(6):684-90. doi: 10.1038/sj.ki.5002731. Epub 2007 Dec 19. Kidney Int. 2008. PMID: 18094678 Free article. Review.

5

CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases.

Bettayeb K, Oumata N, Echalier A, Ferandin Y, Endicott JA, Galons H, Meijer L. Bettayeb K, et al. Among authors: meijer l. Oncogene. 2008 Oct 2;27(44):5797-807. doi: 10.1038/onc.2008.191. Epub 2008 Jun 23. Oncogene. 2008. PMID: 18574471

6

Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.

Oumata N, Bettayeb K, Ferandin Y, Demange L, Lopez-Giral A, Goddard ML, Myrianthopoulos V, Mikros E, Flajolet M, Greengard P, Meijer L, Galons H. Oumata N, et al. Among authors: meijer l. J Med Chem. 2008 Sep 11;51(17):5229-42. doi: 10.1021/jm800109e. Epub 2008 Aug 13. J Med Chem. 2008. PMID: 18698753

7

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine.

Bettayeb K, Sallam H, Ferandin Y, Popowycz F, Fournet G, Hassan M, Echalier A, Bernard P, Endicott J, Joseph B, Meijer L. Bettayeb K, et al. Among authors: meijer l. Mol Cancer Ther. 2008 Sep;7(9):2713-24. doi: 10.1158/1535-7163.MCT-08-0080. Mol Cancer Ther. 2008. PMID: 18790752 Free article.

8

Cyclin-dependent kinase inhibitors: a survey of recent patent literature.

Galons H, Oumata N, Meijer L. Galons H, et al. Among authors: meijer l. Expert Opin Ther Pat. 2010 Mar;20(3):377-404. doi: 10.1517/13543770903524284. Expert Opin Ther Pat. 2010. PMID: 20180621 Review.

9

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells.

Bettayeb K, Baunbæk D, Delehouze C, Loaëc N, Hole AJ, Baumli S, Endicott JA, Douc-Rasy S, Bénard J, Oumata N, Galons H, Meijer L. Bettayeb K, et al. Among authors: meijer l. Genes Cancer. 2010 Apr;1(4):369-80. doi: 10.1177/1947601910369817. Genes Cancer. 2010. PMID: 21779453 Free PMC article.

10

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.

Bettayeb K, Oumata N, Zhang Y, Luo W, Bustos V, Galons H, Greengard P, Meijer L, Flajolet M. Bettayeb K, et al. Among authors: meijer l. FASEB J. 2012 Dec;26(12):5115-23. doi: 10.1096/fj.12-212985. Epub 2012 Sep 12. FASEB J. 2012. PMID: 22972917 Free PMC article.

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