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Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.
Billot K, Coquil C, Villiers B, Josselin-Foll B, Desban N, Delehouzé C, Oumata N, Le Meur Y, Boletta A, Weimbs T, Grosch M, Witzgall R, Saunier S, Fischer E, Pontoglio M, Fautrel A, Mrug M, Wallace D, Tran PV, Trudel M, Bukanov N, Ibraghimov-Beskrovnaya O, Meijer L. Billot K, et al. Among authors: bukanov n. Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F57-F73. doi: 10.1152/ajprenal.00489.2017. Epub 2018 Mar 14. Am J Physiol Renal Physiol. 2018. PMID: 29537311 Free PMC article.
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Husson H, Moreno S, Smith LA, Smith MM, Russo RJ, Pitstick R, Sergeev M, Ledbetter SR, Bukanov NO, Lane M, Zhang K, Billot K, Carlson G, Shah J, Meijer L, Beier DR, Ibraghimov-Beskrovnaya O. Husson H, et al. Among authors: bukanov no. Hum Mol Genet. 2016 Jun 1;25(11):2245-2255. doi: 10.1093/hmg/ddw093. Epub 2016 Apr 5. Hum Mol Genet. 2016. PMID: 27053712 Free PMC article.
Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease.
Natoli TA, Husson H, Rogers KA, Smith LA, Wang B, Budman Y, Bukanov NO, Ledbetter SR, Klinger KW, Leonard JP, Ibraghimov-Beskrovnaya O. Natoli TA, et al. Among authors: bukanov no. Hum Mol Genet. 2012 Aug 1;21(15):3397-407. doi: 10.1093/hmg/dds172. Epub 2012 May 4. Hum Mol Genet. 2012. PMID: 22563011 Free PMC article.
CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis.
Bracken C, Beauverger P, Duclos O, Russo RJ, Rogers KA, Husson H, Natoli TA, Ledbetter SR, Janiak P, Ibraghimov-Beskrovnaya O, Bukanov NO. Bracken C, et al. Among authors: bukanov no. Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1414-22. doi: 10.1152/ajprenal.00426.2015. Epub 2016 Apr 13. Am J Physiol Renal Physiol. 2016. PMID: 27076647 Free article.
46 results