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B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.
Raybuck AL, Cho SH, Li J, Rogers MC, Lee K, Williams CL, Shlomchik M, Thomas JW, Chen J, Williams JV, Boothby MR. Raybuck AL, et al. Among authors: li j. J Immunol. 2018 Apr 15;200(8):2627-2639. doi: 10.4049/jimmunol.1701321. Epub 2018 Mar 12. J Immunol. 2018. PMID: 29531165 Free PMC article.
mTORC1 as a cell-intrinsic rheostat that shapes development, preimmune repertoire, and function of B lymphocytes.
Raybuck AL, Lee K, Cho SH, Li J, Thomas JW, Boothby MR. Raybuck AL, et al. Among authors: li j. FASEB J. 2019 Dec;33(12):13202-13215. doi: 10.1096/fj.201900069R. Epub 2019 Sep 18. FASEB J. 2019. PMID: 31533002 Free PMC article.
The findings also reveal a range in the impact of this nutrient sensor on activity-response relationships for distinct endpoints.-Raybuck, A. L., Lee, K., Cho, S. H., Li, J., Thomas, J. W., Boothby, M. R. mTORC1 as a cell-intrinsic rheostat that shapes develo …
The findings also reveal a range in the impact of this nutrient sensor on activity-response relationships for distinct endpoints.-Raybuck, A …
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