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JNJ-7184, a Respiratory Syncytial Virus inhibitor targeting the connector domain of the viral polymerase.
Bonneux B, Shareef A, Tcherniuk S, Anson B, de Bruyn S, Verheyen N, Thys K, Conceição-Neto N, Van Ginderen M, Kwanten L, Ysebaert N, Vranckx L, Peeters E, Lanckacker E, Gallup JM, Sitthicharoenchai P, Alnajjar S, Ackermann MR, Adhikari S, Bhaumik A, Patrick A, Fung A, Sutto-Ortiz P, Decroly E, Mason SW, Lançois D, Deval J, Jin Z, Eléouët JF, Fearns R, Koul A, Roymans D, Rigaux P, Herschke F. Bonneux B, et al. Among authors: lanckacker e. Antiviral Res. 2024 May 19:105907. doi: 10.1016/j.antiviral.2024.105907. Online ahead of print. Antiviral Res. 2024. PMID: 38772503
A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation.
Joossen C, Baán A, Moreno-Cinos C, Joossens J, Cools N, Lanckacker E, Moons L, Lemmens K, Lambeir AM, Fransen E, Delputte P, Caljon G, Van Der Veken P, Maes L, De Meester I, Kiekens F, Augustyns K, Cos P. Joossen C, et al. Among authors: lanckacker e. Sci Rep. 2020 Oct 14;10(1):17268. doi: 10.1038/s41598-020-74159-w. Sci Rep. 2020. PMID: 33057006 Free PMC article.
A small-molecule fusion inhibitor of influenza virus is orally active in mice.
van Dongen MJP, Kadam RU, Juraszek J, Lawson E, Brandenburg B, Schmitz F, Schepens WBG, Stoops B, van Diepen HA, Jongeneelen M, Tang C, Vermond J, van Eijgen-Obregoso Real A, Blokland S, Garg D, Yu W, Goutier W, Lanckacker E, Klap JM, Peeters DCG, Wu J, Buyck C, Jonckers THM, Roymans D, Roevens P, Vogels R, Koudstaal W, Friesen RHE, Raboisson P, Dhanak D, Goudsmit J, Wilson IA. van Dongen MJP, et al. Among authors: lanckacker e. Science. 2019 Mar 8;363(6431):eaar6221. doi: 10.1126/science.aar6221. Science. 2019. PMID: 30846569 Free PMC article.
Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
Jones HG, Ritschel T, Pascual G, Brakenhoff JPJ, Keogh E, Furmanova-Hollenstein P, Lanckacker E, Wadia JS, Gilman MSA, Williamson RA, Roymans D, van 't Wout AB, Langedijk JP, McLellan JS. Jones HG, et al. Among authors: lanckacker e. PLoS Pathog. 2018 Mar 6;14(3):e1006935. doi: 10.1371/journal.ppat.1006935. eCollection 2018 Mar. PLoS Pathog. 2018. PMID: 29509814 Free PMC article.
Characterizing the in vitro biofilm phenotype of Staphylococcus epidermidis isolates from central venous catheters.
Van Kerckhoven M, Hotterbeekx A, Lanckacker E, Moons P, Lammens C, Kerstens M, Ieven M, Delputte P, Jorens PG, Malhotra-Kumar S, Goossens H, Maes L, Cos P. Van Kerckhoven M, et al. Among authors: lanckacker e. J Microbiol Methods. 2016 Aug;127:95-101. doi: 10.1016/j.mimet.2016.05.009. Epub 2016 May 16. J Microbiol Methods. 2016. PMID: 27196636
A flow cytometric approach to quantify biofilms.
Kerstens M, Boulet G, Van Kerckhoven M, Clais S, Lanckacker E, Delputte P, Maes L, Cos P. Kerstens M, et al. Among authors: lanckacker e. Folia Microbiol (Praha). 2015 Jul;60(4):335-42. doi: 10.1007/s12223-015-0400-4. Epub 2015 May 7. Folia Microbiol (Praha). 2015. PMID: 25948317
20 results