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Pharmacological stimulation of type 5 adenylyl cyclase stabilizes heart rate under both microgravity and hypergravity induced by parabolic flight.
Bai Y, Tsunematsu T, Jiao Q, Ohnuki Y, Mototani Y, Shiozawa K, Jin M, Cai W, Jin HL, Fujita T, Ichikawa Y, Suita K, Kurotani R, Yokoyama U, Sato M, Iwatsubo K, Ishikawa Y, Okumura S. Bai Y, et al. Among authors: mototani y. J Pharmacol Sci. 2012;119(4):381-9. doi: 10.1254/jphs.12102fp. Epub 2012 Jul 31. J Pharmacol Sci. 2012. PMID: 22850613 Free article.
Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses.
Okumura S, Fujita T, Cai W, Jin M, Namekata I, Mototani Y, Jin H, Ohnuki Y, Tsuneoka Y, Kurotani R, Suita K, Kawakami Y, Hamaguchi S, Abe T, Kiyonari H, Tsunematsu T, Bai Y, Suzuki S, Hidaka Y, Umemura M, Ichikawa Y, Yokoyama U, Sato M, Ishikawa F, Izumi-Nakaseko H, Adachi-Akahane S, Tanaka H, Ishikawa Y. Okumura S, et al. Among authors: mototani y. J Clin Invest. 2014 Jun;124(6):2785-801. doi: 10.1172/JCI64784. Epub 2014 Apr 24. J Clin Invest. 2014. PMID: 24892712 Free PMC article.
34 results