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Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes.
Cell Rep. 2018 Jan 30;22(5):1200-1210. doi: 10.1016/j.celrep.2018.01.014.
Cell Rep. 2018.
PMID: 29386108
Free PMC article.
Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer.
Boulware SB, Christensen LA, Thames H, Coghlan L, Vasquez KM, Finch RA.
Boulware SB, et al.
Mol Carcinog. 2014 Sep;53(9):744-52. doi: 10.1002/mc.22026. Epub 2013 May 16.
Mol Carcinog. 2014.
PMID: 23681918
Free PMC article.
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2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.
Boulware S, Fields T, McIvor E, Powell KL, Abel EL, Vasquez KM, MacLeod MC.
Boulware S, et al.
Toxicol Appl Pharmacol. 2012 Sep 1;263(2):203-9. doi: 10.1016/j.taap.2012.06.010. Epub 2012 Jun 23.
Toxicol Appl Pharmacol. 2012.
PMID: 22732900
Free PMC article.
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2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide.
Powell KL, Boulware S, Thames H, Vasquez KM, MacLeod MC.
Powell KL, et al.
Chem Res Toxicol. 2010 Mar 15;23(3):497-503. doi: 10.1021/tx9001918.
Chem Res Toxicol. 2010.
PMID: 20050631
Free PMC article.
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Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog.
Abel EL, Boulware S, Fields T, McIvor E, Powell KL, DiGiovanni J, Vasquez KM, MacLeod MC.
Abel EL, et al.
Toxicol Appl Pharmacol. 2013 Feb 1;266(3):439-42. doi: 10.1016/j.taap.2012.11.020. Epub 2012 Nov 30.
Toxicol Appl Pharmacol. 2013.
PMID: 23201461
Free PMC article.
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