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Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway.
Fitoterapia. 2018 Mar;125:161-173. doi: 10.1016/j.fitote.2018.01.006. Epub 2018 Feb 2.
Fitoterapia. 2018.
PMID: 29355749
Concurrent Reactive Oxygen Species Generation and Aneuploidy Induction Contribute to Thymoquinone Anticancer Activity.
Al-Hayali M, Garces A, Stocks M, Collins H, Bradshaw TD.
Al-Hayali M, et al.
Molecules. 2021 Aug 25;26(17):5136. doi: 10.3390/molecules26175136.
Molecules. 2021.
PMID: 34500570
Free PMC article.
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Codrug Approach for the Potential Treatment of EML4-ALK Positive Lung Cancer.
Garces AE, Al-Hayali M, Lee JB, Li J, Gershkovich P, Bradshaw TD, Stocks MJ.
Garces AE, et al.
ACS Med Chem Lett. 2019 Sep 27;11(3):316-321. doi: 10.1021/acsmedchemlett.9b00378. eCollection 2020 Mar 12.
ACS Med Chem Lett. 2019.
PMID: 32184963
Free PMC article.
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Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system.
Lee JB, Zgair A, Malec J, Kim TH, Kim MG, Ali J, Qin C, Feng W, Chiang M, Gao X, Voronin G, Garces AE, Lau CL, Chan TH, Hume A, McIntosh TM, Soukarieh F, Al-Hayali M, Cipolla E, Collins HM, Heery DM, Shin BS, Yoo SD, Kagan L, Stocks MJ, Bradshaw TD, Fischer PM, Gershkovich P.
Lee JB, et al.
J Control Release. 2018 Sep 28;286:10-19. doi: 10.1016/j.jconrel.2018.07.022. Epub 2018 Jul 18.
J Control Release. 2018.
PMID: 30016732
Free PMC article.
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