Wu JT - Search Results

1

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.

Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF. Hyer ML, et al. Among authors: wu jt. Nat Med. 2018 Feb;24(2):186-193. doi: 10.1038/nm.4474. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334375

2

Endogenous dopamine release in the human brain as a pharmacodynamic biomarker: evaluation of the new GPR139 agonist TAK-041 with [¹¹C]PHNO PET.

Rabiner EA, Uz T, Mansur A, Brown T, Chen G, Wu J, Atienza J, Schwarz AJ, Yin W, Lewis Y, Searle GE, Dennison JMTJ, Passchier J, Gunn RN, Tauscher J. Rabiner EA, et al. Neuropsychopharmacology. 2022 Jun;47(7):1405-1412. doi: 10.1038/s41386-021-01204-1. Epub 2021 Oct 21. Neuropsychopharmacology. 2022. PMID: 34675381 Free PMC article.

3

A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor.

Takano A, Stenkrona P, Stepanov V, Amini N, Martinsson S, Tsai M, Goldsmith P, Xie J, Wu J, Uz T, Halldin C, Macek TA. Takano A, et al. Neuroimage. 2016 Nov 1;141:10-17. doi: 10.1016/j.neuroimage.2016.06.047. Epub 2016 Jul 15. Neuroimage. 2016. PMID: 27423256 Clinical Trial.

4

A phase 3 double-blind randomized (CONSORT-compliant) study of azilsartan medoxomil compared to valsartan in Chinese patients with essential hypertension.

Wu J, Du X, Lv Q, Li Z, Zheng Z, Xia Y, Tang C, Yao Z, Zhang J, Long M, Hisada M, Wu J, Zhou W, Ma C. Wu J, et al. Medicine (Baltimore). 2020 Aug 7;99(32):e21465. doi: 10.1097/MD.0000000000021465. Medicine (Baltimore). 2020. PMID: 32769878 Free PMC article. Clinical Trial.

5

Effects of dexlansoprazole MR, a novel dual delayed release formulation of a proton pump inhibitor, on plasma gastrin levels in healthy subjects.

Zhang W, Wu J, Atkinson SN. Zhang W, et al. J Clin Pharmacol. 2009 Apr;49(4):444-54. doi: 10.1177/0091270008330155. J Clin Pharmacol. 2009. PMID: 19318694 Clinical Trial.

6

Safety, tolerability, pharmacokinetics, and pharmacodynamic properties of the GPR40 agonist TAK-875: results from a double-blind, placebo-controlled single oral dose rising study in healthy volunteers.

Naik H, Vakilynejad M, Wu J, Viswanathan P, Dote N, Higuchi T, Leifke E. Naik H, et al. J Clin Pharmacol. 2012 Jul;52(7):1007-16. doi: 10.1177/0091270011409230. Epub 2011 May 24. J Clin Pharmacol. 2012. PMID: 21610201 Clinical Trial.

7

Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial.

Burns DK, Alexander RC, Welsh-Bohmer KA, Culp M, Chiang C, O'Neil J, Evans RM, Harrigan P, Plassman BL, Burke JR, Wu J, Lutz MW, Haneline S, Schwarz AJ, Schneider LS, Yaffe K, Saunders AM, Ratti E; TOMMORROW study investigators. Burns DK, et al. Lancet Neurol. 2021 Jul;20(7):537-547. doi: 10.1016/S1474-4422(21)00043-0. Lancet Neurol. 2021. PMID: 34146512 Clinical Trial.

8

Effect of hydrochlorothiazide on the pharmacokinetics and pharmacodynamics of febuxostat, a non-purine selective inhibitor of xanthine oxidase.

Grabowski B, Khosravan R, Wu JT, Vernillet L, Lademacher C. Grabowski B, et al. Among authors: wu jt. Br J Clin Pharmacol. 2010 Jul;70(1):57-64. doi: 10.1111/j.1365-2125.2010.03667.x. Br J Clin Pharmacol. 2010. PMID: 20642548 Free PMC article. Clinical Trial.

9

Drug interaction studies with dexlansoprazole modified release (TAK-390MR), a proton pump inhibitor with a dual delayed-release formulation: results of four randomized, double-blind, crossover, placebo-controlled, single-centre studies.

Vakily M, Lee RD, Wu J, Gunawardhana L, Mulford D. Vakily M, et al. Clin Drug Investig. 2009;29(1):35-50. doi: 10.2165/0044011-200929010-00004. Clin Drug Investig. 2009. PMID: 19067473 Clinical Trial.

10

Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level-dependent functional magnetic resonance imaging study in elderly adults.

Knodt AR, Burke JR, Welsh-Bohmer KA, Plassman BL, Burns DK, Brannan SK, Kukulka M, Wu J, Hariri AR. Knodt AR, et al. Alzheimers Dement (N Y). 2019 Jun 26;5:254-263. doi: 10.1016/j.trci.2019.05.004. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31304231 Free PMC article.

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