Sanchez-Garcia E - Search Results

1

Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter Protein.

Ehlers M, Grad JN, Mittal S, Bier D, Mertel M, Ohl L, Bartel M, Briels J, Heimann M, Ottmann C, Sanchez-Garcia E, Hoffmann D, Schmuck C. Ehlers M, et al. Chembiochem. 2018 Mar 16;19(6):591-595. doi: 10.1002/cbic.201700588. Epub 2018 Feb 15. Chembiochem. 2018. PMID: 29282826

2

Molecular tweezers modulate 14-3-3 protein-protein interactions.

Bier D, Rose R, Bravo-Rodriguez K, Bartel M, Ramirez-Anguita JM, Dutt S, Wilch C, Klärner FG, Sanchez-Garcia E, Schrader T, Ottmann C. Bier D, et al. Nat Chem. 2013 Mar;5(3):234-9. doi: 10.1038/nchem.1570. Epub 2013 Feb 17. Nat Chem. 2013. PMID: 23422566

3

Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism.

Lopes DH, Attar A, Nair G, Hayden EY, Du Z, McDaniel K, Dutt S, Bravo-Rodriguez K, Mittal S, Klärner FG, Wang C, Sanchez-Garcia E, Schrader T, Bitan G. Lopes DH, et al. ACS Chem Biol. 2015 Jun 19;10(6):1555-69. doi: 10.1021/acschembio.5b00146. Epub 2015 Apr 16. ACS Chem Biol. 2015. PMID: 25844890

4

Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01.

Vöpel T, Bravo-Rodriguez K, Mittal S, Vachharajani S, Gnutt D, Sharma A, Steinhof A, Fatoba O, Ellrichmann G, Nshanian M, Heid C, Loo JA, Klärner FG, Schrader T, Bitan G, Wanker EE, Ebbinghaus S, Sanchez-Garcia E. Vöpel T, et al. J Am Chem Soc. 2017 Apr 26;139(16):5640-5643. doi: 10.1021/jacs.6b11039. Epub 2017 Apr 13. J Am Chem Soc. 2017. PMID: 28406616 Free PMC article.

5

The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.

Bier D, Mittal S, Bravo-Rodriguez K, Sowislok A, Guillory X, Briels J, Heid C, Bartel M, Wettig B, Brunsveld L, Sanchez-Garcia E, Schrader T, Ottmann C. Bier D, et al. J Am Chem Soc. 2017 Nov 15;139(45):16256-16263. doi: 10.1021/jacs.7b07939. Epub 2017 Nov 2. J Am Chem Soc. 2017. PMID: 29039919 Free PMC article.

6

A Multiperspective Approach to Solvent Regulation of Enzymatic Activity: HMG-CoA Reductase.

Dirkmann M, Iglesias-Fernández J, Muñoz V, Sokkar P, Rumancev C, von Gundlach A, Krenczyk O, Vöpel T, Nowack J, Schroer MA, Ebbinghaus S, Herrmann C, Rosenhahn A, Sanchez-Garcia E, Schulz F. Dirkmann M, et al. Chembiochem. 2018 Jan 18;19(2):153-158. doi: 10.1002/cbic.201700596. Epub 2017 Dec 21. Chembiochem. 2018. PMID: 29139594

7

Molecular recognition of carboxylates in the protein leucine zipper by a multivalent supramolecular ligand: residue-specific, sensitive and label-free probing by UV resonance Raman spectroscopy.

Zakeri B , Niebling S , Martinéz AG , Sokkar P , Sanchez-Garcia E , Schmuck C , Schlücker S . Zakeri B , et al. Phys Chem Chem Phys. 2018 Jan 17;20(3):1817-1820. doi: 10.1039/c7cp04971d. Phys Chem Chem Phys. 2018. PMID: 29292422

8

Mechanism of Inhibition of Beta Amyloid Toxicity by Supramolecular Tweezers.

Mittal S, Bravo-Rodriguez K, Sanchez-Garcia E. Mittal S, et al. J Phys Chem B. 2018 Apr 19;122(15):4196-4205. doi: 10.1021/acs.jpcb.7b10530. Epub 2018 Apr 9. J Phys Chem B. 2018. PMID: 29630377

9

Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.

Yilmaz E, Bier D, Guillory X, Briels J, Ruiz-Blanco YB, Sanchez-Garcia E, Ottmann C, Kaiser M. Yilmaz E, et al. Chemistry. 2018 Sep 18;24(52):13807-13814. doi: 10.1002/chem.201801074. Epub 2018 Aug 22. Chemistry. 2018. PMID: 29924885

10

Solvent-Enhanced Conformational Flexibility of Cyclic Tetrapeptides.

Berger N, Wollny LJB, Sokkar P, Mittal S, Mieres-Perez J, Stoll R, Sander W, Sanchez-Garcia E. Berger N, et al. Chemphyschem. 2019 Jul 2;20(13):1664-1670. doi: 10.1002/cphc.201900345. Epub 2019 Jun 13. Chemphyschem. 2019. PMID: 31045298

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