Qian NX - Search Results

1

Hypoxia and transforming growth factor-beta1 pathway activation promote Chinese Hamster Ovary cell aggregation.

Qian Y, Rehmann MS, Qian NX, He A, Borys MC, Kayne PS, Li ZJ. Qian Y, et al. Among authors: qian nx. Biotechnol Bioeng. 2018 Apr;115(4):1051-1061. doi: 10.1002/bit.26520. Epub 2018 Jan 8. Biotechnol Bioeng. 2018. PMID: 29251349

2

Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells.

Qian Y, Khattak SF, Xing Z, He A, Kayne PS, Qian NX, Pan SH, Li ZJ. Qian Y, et al. Among authors: qian nx. Biotechnol Prog. 2011 Jul;27(4):1190-4. doi: 10.1002/btpr.630. Epub 2011 May 18. Biotechnol Prog. 2011. PMID: 21595052

3

Hypoxia influences protein transport and epigenetic repression of CHO cell cultures in shake flasks.

Qian Y, Xing Z, Lee S, Mackin NA, He A, Kayne PS, He Q, Qian NX, Li ZJ. Qian Y, et al. Among authors: qian nx. Biotechnol J. 2014 Nov;9(11):1413-24. doi: 10.1002/biot.201400315. Epub 2014 Oct 22. Biotechnol J. 2014. PMID: 25271019

4

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media.

Xu J, Rehmann MS, Xu X, Huang C, Tian J, Qian NX, Li ZJ. Xu J, et al. Among authors: qian nx. MAbs. 2018 Apr;10(3):488-499. doi: 10.1080/19420862.2018.1433978. Epub 2018 Feb 20. MAbs. 2018. PMID: 29388872 Free PMC article.

5

Early identification of unusually clustered mutations and root causes in therapeutic antibody development.

Qian Y, Chen Z, Huang X, Wang X, Xu X, Kirov S, Ludwig R, Qian NX, Ravi K, Tao L, Borys MC, Li ZJ. Qian Y, et al. Among authors: qian nx. Biotechnol Bioeng. 2018 Sep;115(9):2377-2382. doi: 10.1002/bit.26728. Epub 2018 Jun 6. Biotechnol Bioeng. 2018. PMID: 29777592

6

Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines.

Tian J, He Q, Oliveira C, Qian Y, Egan S, Xu J, Qian NX, Langsdorf E, Warrack B, Aranibar N, Reily M, Borys M, Li ZJ. Tian J, et al. Among authors: qian nx. Eng Life Sci. 2020 Jan 9;20(3-4):112-125. doi: 10.1002/elsc.201900124. eCollection 2020 Mar. Eng Life Sci. 2020. PMID: 32874175 Free PMC article.

7

Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning.

He Q, Rehmann MS, Tian J, Xu J, Sabino L, Vandermark E, Basson Z, Po I, Bierilo K, Tremml G, Rizzi G, Langsdorf EF, Qian NX, Borys MC, Khetan A, Li ZJ. He Q, et al. Among authors: qian nx. Bioengineering (Basel). 2022 Apr 15;9(4):173. doi: 10.3390/bioengineering9040173. Bioengineering (Basel). 2022. PMID: 35447733 Free PMC article.

8

WITHDRAWN: Aminoglycoside phosphotransferase II gene as primary selection marker for Pichia pastoris producing full-length monoclonal antibody.

Qian Y, Xu X, Qian NX, Dhar V, You L, Xing Z, Huang C, Pan SH, Li ZJ. Qian Y, et al. Among authors: qian nx. Protein Expr Purif. 2012 Sep 5:S1046-5928(12)00238-0. doi: 10.1016/j.pep.2012.08.019. Online ahead of print. Protein Expr Purif. 2012. PMID: 22982086

9

Implementation of Plate Imaging for Demonstration of Monoclonality in Biologics Manufacturing Development.

Zingaro K, Shaw D, Carson J, Mayer-Bartschmid A, Bender C, Alves C, Mcvey D, Qian NX, Wei Q, Laird MW, Zhu Y, Emmins R, Follit JA, Porter A, Racher AJ, Milne S, Carubelli I, Du Z, Khatri A, Failly M, Broly H, Lee F, Reeser M, Spidel J, Anderson K, Demaria C, Di-Carlo J, Gill J, Lundquist A, Kumar SR, Gill T. Zingaro K, et al. Among authors: qian nx. PDA J Pharm Sci Technol. 2018 Jul-Aug;72(4):438-450. doi: 10.5731/pdajpst.2018.008789. Epub 2018 Apr 18. PDA J Pharm Sci Technol. 2018. PMID: 29669815

10

Evidence for coordinate regulation of the A system for amino acid transport and the mRNA for the alpha 1 subunit of the Na+,K(+)-ATPase gene in Chinese hamster ovary cells.

Qian NX, Pastor-Anglada M, Englesberg E. Qian NX, et al. Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3416-20. doi: 10.1073/pnas.88.8.3416. Proc Natl Acad Sci U S A. 1991. PMID: 1849656 Free PMC article.

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