Reynolds DS - Search Results

1

Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABA_A receptor positive allosteric modulator PF-06372865.

Nickolls SA, Gurrell R, van Amerongen G, Kammonen J, Cao L, Brown AR, Stead C, Mead A, Watson C, Hsu C, Owen RM, Pike A, Fish RL, Chen L, Qiu R, Morris ED, Feng G, Whitlock M, Gorman D, van Gerven J, Reynolds DS, Dua P, Butt RP. Nickolls SA, et al. Among authors: reynolds ds. Br J Pharmacol. 2018 Feb;175(4):708-725. doi: 10.1111/bph.14119. Epub 2018 Jan 18. Br J Pharmacol. 2018. PMID: 29214652 Free PMC article. Clinical Trial.

2

Design and Identification of a Novel, Functionally Subtype Selective GABA_A Positive Allosteric Modulator (PF-06372865).

Owen RM, Blakemore D, Cao L, Flanagan N, Fish R, Gibson KR, Gurrell R, Huh CW, Kammonen J, Mortimer-Cassen E, Nickolls SA, Omoto K, Owen D, Pike A, Pryde DC, Reynolds DS, Roeloffs R, Rose C, Stead C, Takeuchi M, Warmus JS, Watson C. Owen RM, et al. Among authors: reynolds ds. J Med Chem. 2019 Jun 27;62(12):5773-5796. doi: 10.1021/acs.jmedchem.9b00322. Epub 2019 Apr 26. J Med Chem. 2019. PMID: 30964988

3

A randomised, placebo-controlled clinical trial with the α2/3/5 subunit selective GABAA positive allosteric modulator PF-06372865 in patients with chronic low back pain.

Gurrell R, Dua P, Feng G, Sudworth M, Whitlock M, Reynolds DS, Butt RP. Gurrell R, et al. Among authors: reynolds ds. Pain. 2018 Sep;159(9):1742-1751. doi: 10.1097/j.pain.0000000000001267. Pain. 2018. PMID: 29787472 Clinical Trial.

4

Photosensitive epilepsy: Robust clinical efficacy of a selective GABA potentiator.

Gurrell R, Gorman D, Whitlock M, Ogden A, Reynolds DS, DiVentura B, Abou-Khalil B, Gelfand M, Pollard J, Hogan RE, Krauss G, Sperling M, Vazquez B, Wechsler RT, Friedman D, Butt RP, French J. Gurrell R, et al. Among authors: reynolds ds. Neurology. 2019 Apr 9;92(15):e1786-e1795. doi: 10.1212/WNL.0000000000007271. Epub 2019 Mar 15. Neurology. 2019. PMID: 30877186 Clinical Trial.

5

The value of genetic and pharmacological approaches to understanding the complexities of GABA(A) receptor subtype functions: the anxiolytic effects of benzodiazepines.

Reynolds DS. Reynolds DS. Pharmacol Biochem Behav. 2008 Jul;90(1):37-42. doi: 10.1016/j.pbb.2008.03.015. Epub 2008 Mar 28. Pharmacol Biochem Behav. 2008. PMID: 18457867 Review.

6

Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.

Winchester WJ, Gore K, Glatt S, Petit W, Gardiner JC, Conlon K, Postlethwaite M, Saintot PP, Roberts S, Gosset JR, Matsuura T, Andrews MD, Glossop PA, Palmer MJ, Clear N, Collins S, Beaumont K, Reynolds DS. Winchester WJ, et al. Among authors: reynolds ds. J Pharmacol Exp Ther. 2014 Nov;351(2):259-69. doi: 10.1124/jpet.114.216010. Epub 2014 Aug 14. J Pharmacol Exp Ther. 2014. PMID: 25125580 Clinical Trial.

7

Assessment of 'active investigation' as a potential measure of female sexual incentive motivation in a preclinical non-contact rodent model: observations with apomorphine.

Hawcock AB, Dawkins TE, Reynolds DS. Hawcock AB, et al. Among authors: reynolds ds. Pharmacol Biochem Behav. 2010 Apr;95(2):179-86. doi: 10.1016/j.pbb.2010.01.002. Epub 2010 Jan 21. Pharmacol Biochem Behav. 2010. PMID: 20096723

8

Potentiation of reflex erectile responses in the anaesthetized rat by the selective melanocortin receptor 4 agonist MB243.

Allard J, Reynolds DS, Edmunds NJ. Allard J, et al. Among authors: reynolds ds. BJU Int. 2008 Sep;102(8):1029-33. doi: 10.1111/j.1464-410X.2008.07751.x. Epub 2008 May 20. BJU Int. 2008. PMID: 18494830

9

II. Slow oscillations in vaginal blood flow: regulation of vaginal blood flow patterns in rat by central and autonomic mechanisms.

Allers KA, Richards N, Scott L, Sweatman C, Cheung J, Reynolds D, Casey JH, Wayman C. Allers KA, et al. J Sex Med. 2010 Mar;7(3):1088-103. doi: 10.1111/j.1743-6109.2009.01466.x. Epub 2009 Aug 28. J Sex Med. 2010. PMID: 19732309

10

Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases.

Benn CL, Gibson KR, Reynolds DS. Benn CL, et al. Among authors: reynolds ds. J Huntingtons Dis. 2021;10(1):203-220. doi: 10.3233/JHD-200421. J Huntingtons Dis. 2021. PMID: 32925081 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

82 results

Search Page