Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

30 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1).
Jørgensen L, Al-Khawaja A, Kickinger S, Vogensen SB, Skovgaard-Petersen J, Rosenthal E, Borkar N, Löffler R, Madsen KK, Bräuner-Osborne H, Schousboe A, Ecker GF, Wellendorph P, Clausen RP. Jørgensen L, et al. Among authors: loffler r. J Med Chem. 2017 Nov 9;60(21):8834-8846. doi: 10.1021/acs.jmedchem.7b00924. Epub 2017 Oct 19. J Med Chem. 2017. PMID: 28991462
Pharmacological Characterization of [3H]ATPCA as a Substrate for Studying the Functional Role of the Betaine/GABA Transporter 1 and the Creatine Transporter.
Al-Khawaja A, Haugaard AS, Marek A, Löffler R, Thiesen L, Santiveri M, Damgaard M, Bundgaard C, Frølund B, Wellendorph P. Al-Khawaja A, et al. Among authors: loffler r. ACS Chem Neurosci. 2018 Mar 21;9(3):545-554. doi: 10.1021/acschemneuro.7b00351. Epub 2017 Nov 22. ACS Chem Neurosci. 2018. PMID: 29131576
Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors.
Kickinger S, Al-Khawaja A, Haugaard AS, Lie MEK, Bavo F, Löffler R, Damgaard M, Ecker GF, Frølund B, Wellendorph P. Kickinger S, et al. Among authors: loffler r. Sci Rep. 2020 Aug 3;10(1):12992. doi: 10.1038/s41598-020-69908-w. Sci Rep. 2020. PMID: 32747622 Free PMC article.
Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters.
Giraudo A, Krall J, Bavo F, Nielsen B, Kongstad KT, Rolando B, De Blasio R, Gloriam DE, Löffler R, Thiesen L, Harpsøe K, Frydenvang K, Boschi D, Wellendorph P, Lolli ML, Jensen AA, Frølund B. Giraudo A, et al. Among authors: loffler r. J Med Chem. 2019 Jun 27;62(12):5797-5809. doi: 10.1021/acs.jmedchem.9b00026. Epub 2019 Jun 5. J Med Chem. 2019. PMID: 31117514 Free article.
Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based γ-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect.
Bavo F, de-Jong H, Petersen J, Falk-Petersen CB, Löffler R, Sparrow E, Rostrup F, Eliasen JN, Wilhelmsen KS, Barslund K, Bundgaard C, Nielsen B, Kristiansen U, Wellendorph P, Bogdanov Y, Frølund B. Bavo F, et al. Among authors: loffler r. J Med Chem. 2021 Dec 23;64(24):17795-17812. doi: 10.1021/acs.jmedchem.1c00290. Epub 2021 Dec 15. J Med Chem. 2021. PMID: 34908407
Survival strategies of artificial active agents.
Zanovello L, Löffler RJG, Caraglio M, Franosch T, Hanczyc MM, Faccioli P. Zanovello L, et al. Among authors: loffler rjg. Sci Rep. 2023 Apr 6;13(1):5616. doi: 10.1038/s41598-023-32267-3. Sci Rep. 2023. PMID: 37024516 Free PMC article.
30 results