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Page 1
Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
Llona-Minguez S, Höglund A, Ghassemian A, Desroses M, Calderón-Montaño JM, Burgos Morón E, Valerie NCK, Wiita E, Almlöf I, Koolmeister T, Mateus A, Cazares-Körner C, Sanjiv K, Homan E, Loseva O, Baranczewski P, Darabi M, Mehdizadeh A, Fayezi S, Jemth AS, Warpman Berglund U, Sigmundsson K, Lundbäck T, Jenmalm Jensen A, Artursson P, Scobie M, Helleday T. Llona-Minguez S, et al. J Med Chem. 2017 Sep 14;60(17):7614. doi: 10.1021/acs.jmedchem.7b01137. Epub 2017 Sep 1. J Med Chem. 2017. PMID: 28862438 No abstract available.
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
Llona-Minguez S, Höglund A, Ghassemian A, Desroses M, Calderón-Montaño JM, Burgos Morón E, Valerie NCK, Wiita E, Almlöf I, Koolmeister T, Mateus A, Cazares-Körner C, Sanjiv K, Homan E, Loseva O, Baranczewski P, Darabi M, Mehdizadeh A, Fayezi S, Jemth AS, Warpman Berglund U, Sigmundsson K, Lundbäck T, Jenmalm Jensen A, Artursson P, Scobie M, Helleday T. Llona-Minguez S, et al. J Med Chem. 2017 May 25;60(10):4279-4292. doi: 10.1021/acs.jmedchem.7b00182. Epub 2017 May 16. J Med Chem. 2017. PMID: 28508636
Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.
Llona-Minguez S, Höglund A, Wiita E, Almlöf I, Mateus A, Calderón-Montaño JM, Cazares-Körner C, Homan E, Loseva O, Baranczewski P, Jemth AS, Häggblad M, Martens U, Lundgren B, Artursson P, Lundbäck T, Jenmalm Jensen A, Warpman Berglund U, Scobie M, Helleday T. Llona-Minguez S, et al. J Med Chem. 2017 Mar 9;60(5):2148-2154. doi: 10.1021/acs.jmedchem.6b01786. Epub 2017 Feb 15. J Med Chem. 2017. PMID: 28145708
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.
Llona-Minguez S, Höglund A, Jacques SA, Johansson L, Calderón-Montaño JM, Claesson M, Loseva O, Valerie NCK, Lundbäck T, Piedrafita J, Maga G, Crespan E, Meijer L, Morón EB, Baranczewski P, Hagbjörk AL, Svensson R, Wiita E, Almlöf I, Visnes T, Jeppsson F, Sigmundsson K, Jensen AJ, Artursson P, Jemth AS, Stenmark P, Berglund UW, Scobie M, Helleday T. Llona-Minguez S, et al. J Med Chem. 2016 Feb 11;59(3):1140-1148. doi: 10.1021/acs.jmedchem.5b01741. Epub 2016 Jan 27. J Med Chem. 2016. PMID: 26771665 Free PMC article.
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Page BDG, Valerie NCK, Wright RHG, Wallner O, Isaksson R, Carter M, Rudd SG, Loseva O, Jemth AS, Almlöf I, Font-Mateu J, Llona-Minguez S, Baranczewski P, Jeppsson F, Homan E, Almqvist H, Axelsson H, Regmi S, Gustavsson AL, Lundbäck T, Scobie M, Strömberg K, Stenmark P, Beato M, Helleday T. Page BDG, et al. Among authors: llona minguez s. Nat Commun. 2019 Nov 1;10(1):5050. doi: 10.1038/s41467-019-12806-1. Nat Commun. 2019. PMID: 31676755 Free PMC article.
Chemical strategies for development of ATR inhibitors.
Llona-Minguez S, Höglund A, Jacques SA, Koolmeister T, Helleday T. Llona-Minguez S, et al. Expert Rev Mol Med. 2014 May 9;16:e10. doi: 10.1017/erm.2014.10. Expert Rev Mol Med. 2014. PMID: 24810715 Review.
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