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Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity.
Kleczko EK, Hinz TK, Nguyen TT, Gurule NJ, Navarro A, Le AT, Johnson AM, Kwak J, Polhac DI, Clambey ET, Weiser-Evans M, Merrick DT, Yang MC, Patil T, Schenk EL, Heasley LE, Nemenoff RA. Kleczko EK, et al. Among authors: nguyen tt. NPJ Precis Oncol. 2023 Feb 4;7(1):15. doi: 10.1038/s41698-023-00355-2. NPJ Precis Oncol. 2023. PMID: 36739466 Free PMC article.
ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.
Aisner DL, Nguyen TT, Paskulin DD, Le AT, Haney J, Schulte N, Chionh F, Hardingham J, Mariadason J, Tebbutt N, Doebele RC, Weickhardt AJ, Varella-Garcia M. Aisner DL, et al. Among authors: nguyen tt. Mol Cancer Res. 2014 Jan;12(1):111-8. doi: 10.1158/1541-7786.MCR-13-0479-T. Epub 2013 Dec 2. Mol Cancer Res. 2014. PMID: 24296758 Free PMC article. Clinical Trial.
Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry.
Nguyen TT, Shin DH, Sohoni S, Singh SK, Rivera-Molina Y, Jiang H, Fan X, Gumin J, Lang FF, Alvarez-Breckenridge C, Godoy-Vitorino F, Zhu L, Zheng WJ, Zhai L, Ladomersky E, Lauing KL, Alonso MM, Wainwright DA, Gomez-Manzano C, Fueyo J. Nguyen TT, et al. J Immunother Cancer. 2022 Jul;10(7):e004935. doi: 10.1136/jitc-2022-004935. J Immunother Cancer. 2022. PMID: 35902132 Free PMC article.
Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.
Jiang H, Shin DH, Nguyen TT, Fueyo J, Fan X, Henry V, Carrillo CC, Yi Y, Alonso MM, Collier TL, Yuan Y, Lang FF, Gomez-Manzano C. Jiang H, et al. Among authors: nguyen tt. Clin Cancer Res. 2019 Nov 15;25(22):6801-6814. doi: 10.1158/1078-0432.CCR-19-0405. Epub 2019 Aug 27. Clin Cancer Res. 2019. PMID: 31455679 Free PMC article.
4,096 results