Habib T - Search Results

1

The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.

Metzler G, Dai X, Thouvenel CD, Khim S, Habib T, Buckner JH, Rawlings DJ. Metzler G, et al. Among authors: habib t. J Immunol. 2017 Oct 1;199(7):2249-2260. doi: 10.4049/jimmunol.1700601. Epub 2017 Aug 11. J Immunol. 2017. PMID: 28801357 Free PMC article.

2

Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant.

Habib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi AK, Luning Prak ET, Meyer-Bahlburg A, Sanda S, Greenbaum C, Rawlings DJ, Buckner JH. Habib T, et al. J Immunol. 2012 Jan 1;188(1):487-96. doi: 10.4049/jimmunol.1102176. Epub 2011 Nov 21. J Immunol. 2012. PMID: 22105996 Free PMC article. Clinical Trial.

3

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.

Dai X, James RG, Habib T, Singh S, Jackson S, Khim S, Moon RT, Liggitt D, Wolf-Yadlin A, Buckner JH, Rawlings DJ. Dai X, et al. Among authors: habib t. J Clin Invest. 2013 May;123(5):2024-36. doi: 10.1172/JCI66963. Epub 2013 Apr 24. J Clin Invest. 2013. PMID: 23619366 Free PMC article.

4

Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling.

Arechiga AF, Habib T, He Y, Zhang X, Zhang ZY, Funk A, Buckner JH. Arechiga AF, et al. Among authors: habib t. J Immunol. 2009 Mar 15;182(6):3343-7. doi: 10.4049/jimmunol.0713370. J Immunol. 2009. PMID: 19265110 Free PMC article.

5

Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes.

Ge Y, Onengut-Gumuscu S, Quinlan AR, Mackey AJ, Wright JA, Buckner JH, Habib T, Rich SS, Concannon P. Ge Y, et al. Among authors: habib t. Diabetes. 2016 Mar;65(3):794-802. doi: 10.2337/db15-0322. Epub 2015 Dec 2. Diabetes. 2016. PMID: 26631741 Free PMC article.

6

Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.

Habib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum C, Buckner JH; Type 1 Diabetes TrialNet Study Group. Habib T, et al. Diabetes. 2019 Jun;68(6):1240-1250. doi: 10.2337/db18-1081. Epub 2019 Mar 20. Diabetes. 2019. PMID: 30894366 Free PMC article.

7

The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.

Dam EM, Habib T, Chen J, Funk A, Glukhova V, Davis-Pickett M, Wei S, James R, Buckner JH, Cerosaletti K. Dam EM, et al. Among authors: habib t. Clin Immunol. 2016 Dec;173:171-180. doi: 10.1016/j.clim.2016.10.018. Epub 2016 Nov 2. Clin Immunol. 2016. PMID: 27816669 Free PMC article.

8

Myc stimulates B lymphocyte differentiation and amplifies calcium signaling.

Habib T, Park H, Tsang M, de Alborán IM, Nicks A, Wilson L, Knoepfler PS, Andrews S, Rawlings DJ, Eisenman RN, Iritani BM. Habib T, et al. J Cell Biol. 2007 Nov 19;179(4):717-31. doi: 10.1083/jcb.200704173. Epub 2007 Nov 12. J Cell Biol. 2007. PMID: 17998397 Free PMC article.

9

Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes.

Miyakawa Y, Rojnuckarin P, Habib T, Kaushansky K. Miyakawa Y, et al. Among authors: habib t. J Biol Chem. 2001 Jan 26;276(4):2494-502. doi: 10.1074/jbc.M002633200. Epub 2000 Oct 27. J Biol Chem. 2001. PMID: 11054408 Free article.

10

The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3.

Habib T, Senadheera S, Weinberg K, Kaushansky K. Habib T, et al. Biochemistry. 2002 Jul 9;41(27):8725-31. doi: 10.1021/bi0202023. Biochemistry. 2002. PMID: 12093291

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