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Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Zhang S, Song X, Cao D, Xu Z, Fan B, Che L, Hu J, Chen B, Dong M, Pilo MG, Cigliano A, Evert K, Ribback S, Dombrowski F, Pascale RM, Cossu A, Vidili G, Porcu A, Simile MM, Pes GM, Giannelli G, Gordan J, Wei L, Evert M, Cong W, Calvisi DF, Chen X. Zhang S, et al. Among authors: che l. J Hepatol. 2017 Dec;67(6):1194-1203. doi: 10.1016/j.jhep.2017.07.006. Epub 2017 Jul 19. J Hepatol. 2017. PMID: 28733220 Free PMC article.
Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis.
Wang H, Wang J, Zhang S, Jia J, Liu X, Zhang J, Wang P, Song X, Che L, Liu K, Ribback S, Cigliano A, Evert M, Wu H, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Among authors: che l. Cell Mol Gastroenterol Hepatol. 2021;11(4):1095-1117. doi: 10.1016/j.jcmgh.2020.11.008. Epub 2020 Nov 21. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33232824 Free PMC article.
Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes-Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.
Wang H, Song X, Liao H, Wang P, Zhang Y, Che L, Zhang J, Zhou Y, Cigliano A, Ament C, Superville D, Ribback S, Reeves M, Pes GM, Liang B, Wu H, Evert M, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Among authors: che l. Hepatology. 2021 Jul;74(1):248-263. doi: 10.1002/hep.31692. Epub 2021 Jun 15. Hepatology. 2021. PMID: 33368437 Free PMC article.
Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
Wang J, Dong M, Xu Z, Song X, Zhang S, Qiao Y, Che L, Gordan J, Hu K, Liu Y, Calvisi DF, Chen X. Wang J, et al. Among authors: che l. Oncogene. 2018 Jun;37(24):3229-3242. doi: 10.1038/s41388-018-0188-1. Epub 2018 Mar 16. Oncogene. 2018. PMID: 29545603 Free PMC article.
829 results