Hardingham GE - Search Results

1

Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.

McQueen J, Ryan TJ, McKay S, Marwick K, Baxter P, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJA, Grant SGN, McColl BW, Komiyama NH, Hardingham GE. McQueen J, et al. Among authors: hardingham ge. Elife. 2017 Jul 21;6:e17161. doi: 10.7554/eLife.17161. Elife. 2017. PMID: 28731405 Free PMC article.

2

Pro-survival signalling from the NMDA receptor.

Hardingham GE. Hardingham GE. Biochem Soc Trans. 2006 Nov;34(Pt 5):936-8. doi: 10.1042/BST0340936. Biochem Soc Trans. 2006. PMID: 17052231 Free PMC article.

3

Compartmentalized NMDA receptor signalling to survival and death.

Soriano FX, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. J Physiol. 2007 Oct 15;584(Pt 2):381-7. doi: 10.1113/jphysiol.2007.138875. Epub 2007 Aug 9. J Physiol. 2007. PMID: 17690142 Free PMC article.

4

The dichotomy of NMDA receptor signaling.

Papadia S, Hardingham GE. Papadia S, et al. Among authors: hardingham ge. Neuroscientist. 2007 Dec;13(6):572-9. doi: 10.1177/10738584070130060401. Neuroscientist. 2007. PMID: 18000068 Free PMC article. Review.

5

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.

Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE. Papadia S, et al. Among authors: hardingham ge. Nat Neurosci. 2008 Apr;11(4):476-87. doi: 10.1038/nn2071. Epub 2008 Mar 23. Nat Neurosci. 2008. PMID: 18344994 Free PMC article.

6

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death.

Martel MA, Wyllie DJ, Hardingham GE. Martel MA, et al. Among authors: hardingham ge. Neuroscience. 2009 Jan 12;158(1):334-43. doi: 10.1016/j.neuroscience.2008.01.080. Epub 2008 Mar 4. Neuroscience. 2009. PMID: 18378405 Free PMC article.

7

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione.

Soriano FX, Léveillé F, Papadia S, Higgins LG, Varley J, Baxter P, Hayes JD, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. J Neurochem. 2008 Oct;107(2):533-43. doi: 10.1111/j.1471-4159.2008.05648.x. Epub 2008 Sep 16. J Neurochem. 2008. PMID: 18761713 Free PMC article.

8

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand.

Soriano FX, Martel MA, Papadia S, Vaslin A, Baxter P, Rickman C, Forder J, Tymianski M, Duncan R, Aarts M, Clarke P, Wyllie DJ, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. J Neurosci. 2008 Oct 15;28(42):10696-710. doi: 10.1523/JNEUROSCI.1207-08.2008. J Neurosci. 2008. PMID: 18923045 Free PMC article.

9

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression.

Martel MA, Soriano FX, Baxter P, Rickman C, Duncan R, Wyllie DJ, Hardingham GE. Martel MA, et al. Among authors: hardingham ge. Channels (Austin). 2009 Jan-Feb;3(1):12-5. doi: 10.4161/chan.3.1.7864. Epub 2009 Jan 16. Channels (Austin). 2009. PMID: 19221512

10

Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin.

Soriano FX, Baxter P, Murray LM, Sporn MB, Gillingwater TH, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. Mol Cells. 2009 Mar 31;27(3):279-82. doi: 10.1007/s10059-009-0050-y. Epub 2009 Mar 19. Mol Cells. 2009. PMID: 19326073 Free PMC article. Review.

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