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Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis.
Yuan Z, van Delft MF, Li MX, Sumardy F, Smith BJ, Huang DCS, Lessene G, Khakam Y, Jin R, He S, Smith NA, Birkinshaw RW, Czabotar PE, Dewson G. Yuan Z, et al. Among authors: huang dcs. PLoS Biol. 2024 May 2;22(5):e3002617. doi: 10.1371/journal.pbio.3002617. eCollection 2024 May. PLoS Biol. 2024. PMID: 38696533 Free PMC article.
Aspirin exposure and its association with metal stent patency in malignant distal biliary obstruction: a large international multicenter propensity score-matched study.
Candido K, Bouchard S, Hansen-Barkun C, Huang DC, Chatterjee A, Menard C, Miller C, Sandha G, Donnellan F, Telford J, Desilets E, Forbes N, Roy A, Calo N, Gan I, Lam E, Pleskow D, Chen Kiow JL, Sarker A, Cadieux-Genesse E, Jain A, Louis F, Bilal M, Sene PM, Fairclough J, Reuangrith J, Benmassaoud A, Geraci O, Martel M, Chen YI. Candido K, et al. Among authors: huang dc. Gastrointest Endosc. 2024 Apr;99(4):557-565. doi: 10.1016/j.gie.2023.11.004. Epub 2023 Nov 10. Gastrointest Endosc. 2024. PMID: 37951281
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells.
Wang Z, Burigotto M, Ghetti S, Vaillant F, Tan T, Capaldo BD, Palmieri M, Hirokawa Y, Tai L, Simpson DS, Chang C, Huang AS, Lieschke E, Diepstraten ST, Kaloni D, Riffkin C, Huang DCS, Li Wai Suen CSN, Garnham AL, Gibbs P, Visvader JE, Sieber OM, Herold MJ, Fava LL, Kelly GL, Strasser A. Wang Z, et al. Among authors: huang dcs. Cancer Discov. 2024 Feb 8;14(2):362-379. doi: 10.1158/2159-8290.CD-23-0402. Cancer Discov. 2024. PMID: 37877779 Free PMC article.
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase.
Pierotti CL, Jacobsen AV, Grohmann C, Dempsey RK, Etemadi N, Hildebrand JM, Fitzgibbon C, Young SN, Davies KA, Kersten WJA, Silke J, Lowes KN, Jousset Sabroux H, Huang DCS, van Delft MF, Murphy JM, Lessene G. Pierotti CL, et al. Among authors: huang dcs. Biochem J. 2023 May 15;480(9):665-684. doi: 10.1042/BCJ20230035. Biochem J. 2023. PMID: 37115711 Free PMC article.
297 results