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Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density.
Lemoine MD, Mannhardt I, Breckwoldt K, Prondzynski M, Flenner F, Ulmer B, Hirt MN, Neuber C, Horváth A, Kloth B, Reichenspurner H, Willems S, Hansen A, Eschenhagen T, Christ T. Lemoine MD, et al. Among authors: mannhardt i. Sci Rep. 2017 Jul 14;7(1):5464. doi: 10.1038/s41598-017-05600-w. Sci Rep. 2017. PMID: 28710467 Free PMC article.
Human Engineered Heart Tissue: Analysis of Contractile Force.
Mannhardt I, Breckwoldt K, Letuffe-Brenière D, Schaaf S, Schulz H, Neuber C, Benzin A, Werner T, Eder A, Schulze T, Klampe B, Christ T, Hirt MN, Huebner N, Moretti A, Eschenhagen T, Hansen A. Mannhardt I, et al. Stem Cell Reports. 2016 Jul 12;7(1):29-42. doi: 10.1016/j.stemcr.2016.04.011. Epub 2016 May 19. Stem Cell Reports. 2016. PMID: 27211213 Free PMC article.
Differentiation of cardiomyocytes and generation of human engineered heart tissue.
Breckwoldt K, Letuffe-Brenière D, Mannhardt I, Schulze T, Ulmer B, Werner T, Benzin A, Klampe B, Reinsch MC, Laufer S, Shibamiya A, Prondzynski M, Mearini G, Schade D, Fuchs S, Neuber C, Krämer E, Saleem U, Schulze ML, Rodriguez ML, Eschenhagen T, Hansen A. Breckwoldt K, et al. Among authors: mannhardt i. Nat Protoc. 2017 Jun;12(6):1177-1197. doi: 10.1038/nprot.2017.033. Epub 2017 May 11. Nat Protoc. 2017. PMID: 28492526
Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes.
Horváth A, Lemoine MD, Löser A, Mannhardt I, Flenner F, Uzun AU, Neuber C, Breckwoldt K, Hansen A, Girdauskas E, Reichenspurner H, Willems S, Jost N, Wettwer E, Eschenhagen T, Christ T. Horváth A, et al. Among authors: mannhardt i. Stem Cell Reports. 2018 Mar 13;10(3):822-833. doi: 10.1016/j.stemcr.2018.01.012. Epub 2018 Feb 8. Stem Cell Reports. 2018. PMID: 29429959 Free PMC article.
Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes-An Artifact by Big Conductance Calcium Activated Potassium Current (Ibk,Ca).
Horváth A, Christ T, Koivumäki JT, Prondzynski M, Zech ATL, Spohn M, Saleem U, Mannhardt I, Ulmer B, Girdauskas E, Meyer C, Hansen A, Eschenhagen T, Lemoine MD. Horváth A, et al. Among authors: mannhardt i. Cells. 2020 Jan 20;9(1):253. doi: 10.3390/cells9010253. Cells. 2020. PMID: 31968557 Free PMC article.
30 results