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Clinical drug resistance linked to interconvertible phenotypic and functional states of tumor-propagating cells in multiple myeloma.
Chaidos A, Barnes CP, Cowan G, May PC, Melo V, Hatjiharissi E, Papaioannou M, Harrington H, Doolittle H, Terpos E, Dimopoulos M, Abdalla S, Yarranton H, Naresh K, Foroni L, Reid A, Rahemtulla A, Stumpf M, Roberts I, Karadimitris A. Chaidos A, et al. Among authors: papaioannou m. Blood. 2013 Jan 10;121(2):318-28. doi: 10.1182/blood-2012-06-436220. Epub 2012 Nov 20. Blood. 2013. PMID: 23169779 Free article.
Transcriptional and epigenetic basis for restoration of G6PD enzymatic activity in human G6PD-deficient cells.
Makarona K, Caputo VS, Costa JR, Liu B, O'Connor D, Iskander D, Roper D, Robertson L, Bhatnagar N, Terpos E, Georgiou E, Papaioannou M, Layton DM, Luzzatto L, Roberts I, Karadimitris A. Makarona K, et al. Among authors: papaioannou m. Blood. 2014 Jul 3;124(1):134-41. doi: 10.1182/blood-2014-02-553792. Epub 2014 May 7. Blood. 2014. PMID: 24805191 Free article.
Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease.
Ersek A, Xu K, Antonopoulos A, Butters TD, Santo AE, Vattakuzhi Y, Williams LM, Goudevenou K, Danks L, Freidin A, Spanoudakis E, Parry S, Papaioannou M, Hatjiharissi E, Chaidos A, Alonzi DS, Twigg G, Hu M, Dwek RA, Haslam SM, Roberts I, Dell A, Rahemtulla A, Horwood NJ, Karadimitris A. Ersek A, et al. Among authors: papaioannou m. J Clin Invest. 2015 Jun;125(6):2279-92. doi: 10.1172/JCI59987. Epub 2015 Apr 27. J Clin Invest. 2015. PMID: 25915583 Free PMC article.
Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma.
Alvarez-Benayas J, Trasanidis N, Katsarou A, Ponnusamy K, Chaidos A, May PC, Xiao X, Bua M, Atta M, Roberts IAG, Auner HW, Hatjiharissi E, Papaioannou M, Caputo VS, Sudbery IM, Karadimitris A. Alvarez-Benayas J, et al. Among authors: papaioannou m. Nat Commun. 2021 Sep 14;12(1):5450. doi: 10.1038/s41467-021-25704-2. Nat Commun. 2021. PMID: 34521827 Free PMC article.
MAF functions as a pioneer transcription factor that initiates and sustains myelomagenesis.
Katsarou A, Trasanidis N, Ponnusamy K, Kostopoulos IV, Alvarez-Benayas J, Papaleonidopoulou F, Keren K, Sabbattini PMR, Feldhahn N, Papaioannou M, Hatjiharissi E, Sudbery IM, Chaidos A, Caputo VS, Karadimitris A. Katsarou A, et al. Among authors: papaioannou m. Blood Adv. 2023 Nov 14;7(21):6395-6410. doi: 10.1182/bloodadvances.2023009772. Blood Adv. 2023. PMID: 37224458 Free PMC article.
231 results