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The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.
Gorman JA, Hundhausen C, Errett JS, Stone AE, Allenspach EJ, Ge Y, Arkatkar T, Clough C, Dai X, Khim S, Pestal K, Liggitt D, Cerosaletti K, Stetson DB, James RG, Oukka M, Concannon P, Gale M Jr, Buckner JH, Rawlings DJ. Gorman JA, et al. Among authors: pestal k. Nat Immunol. 2017 Jul;18(7):744-752. doi: 10.1038/ni.3766. Epub 2017 May 29. Nat Immunol. 2017. PMID: 28553952 Free PMC article.
Intracellular Nucleic Acid Detection in Autoimmunity.
Crowl JT, Gray EE, Pestal K, Volkman HE, Stetson DB. Crowl JT, et al. Among authors: pestal k. Annu Rev Immunol. 2017 Apr 26;35:313-336. doi: 10.1146/annurev-immunol-051116-052331. Epub 2017 Jan 30. Annu Rev Immunol. 2017. PMID: 28142323 Free PMC article. Review.
Regulation of the nucleic acid-sensing Toll-like receptors.
Lind NA, Rael VE, Pestal K, Liu B, Barton GM. Lind NA, et al. Among authors: pestal k. Nat Rev Immunol. 2022 Apr;22(4):224-235. doi: 10.1038/s41577-021-00577-0. Epub 2021 Jul 16. Nat Rev Immunol. 2022. PMID: 34272507 Free PMC article. Review.
A selective role of NKG2D in inflammatory and autoimmune diseases.
Guerra N, Pestal K, Juarez T, Beck J, Tkach K, Wang L, Raulet DH. Guerra N, et al. Among authors: pestal k. Clin Immunol. 2013 Dec;149(3):432-9. doi: 10.1016/j.clim.2013.09.003. Epub 2013 Sep 14. Clin Immunol. 2013. PMID: 24211717 Free PMC article.
Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.
Hamilton JR, Stahl EC, Tsuchida CA, Lin-Shiao E, Tsui CK, Pestal K, Gildea HK, Witkowsky LB, Moehle EA, McDevitt SL, McElroy M, Keller A, Sylvain I, Hirsh A, Ciling A, Ehrenberg AJ, Ringeisen BR, Huberty G, Urnov FD, Giannikopoulos P, Doudna JA; IGI SARS-CoV-2 Consortium. Hamilton JR, et al. Among authors: pestal k. PLoS One. 2021 Aug 5;16(8):e0255690. doi: 10.1371/journal.pone.0255690. eCollection 2021. PLoS One. 2021. PMID: 34351984 Free PMC article.
Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus.
Ehrenberg AJ, Moehle EA, Brook CE, Doudna Cate AH, Witkowsky LB, Sachdeva R, Hirsh A, Barry K, Hamilton JR, Lin-Shiao E, McDevitt S, Valentin-Alvarado L, Letourneau KN, Hunter L, Keller A, Pestal K, Frankino PA, Murley A, Nandakumar D, Stahl EC, Tsuchida CA, Gildea HK, Murdock AG, Hochstrasser ML, O'Brien E, Ciling A, Tsitsiklis A, Worden K, Dugast-Darzacq C, Hays SG, Barber CC, McGarrigle R, Lam EK, Ensminger DC, Bardet L, Sherry C, Harte A, Nicolette G, Giannikopoulos P, Hockemeyer D, Petersen M, Urnov FD, Ringeisen BR, Boots M, Doudna JA; IGI SARS-CoV-2 Testing Consortium. Ehrenberg AJ, et al. Among authors: pestal k. PLoS One. 2021 May 26;16(5):e0251296. doi: 10.1371/journal.pone.0251296. eCollection 2021. PLoS One. 2021. PMID: 34038425 Free PMC article.
LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples.
Stahl EC, Gopez AR, Tsuchida CA, Fan VB, Moehle EA, Witkowsky LB, Hamilton JR, Lin-Shiao E, McElroy M, McDevitt SL, Ciling A, Tsui CK, Pestal K, Gildea HK, Keller A, Sylvain IA, Williams C, Hirsh A, Ehrenberg AJ, Kantor R, Metzger M, Nelson KL, Urnov FD, Ringeisen BR, Giannikopoulos P, Doudna JA; IGI Testing Consortium. Stahl EC, et al. Among authors: pestal k. PLoS One. 2021 Nov 10;16(11):e0258263. doi: 10.1371/journal.pone.0258263. eCollection 2021. PLoS One. 2021. PMID: 34758033 Free PMC article.
15 results