McShan AC - Search Results

1

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role.

Natarajan K, McShan AC, Jiang J, Kumirov VK, Wang R, Zhao H, Schuck P, Tilahun ME, Boyd LF, Ying J, Bax A, Margulies DH, Sgourakis NG. Natarajan K, et al. Among authors: mcshan ac. Nat Commun. 2017 May 16;8:15260. doi: 10.1038/ncomms15260. Nat Commun. 2017. PMID: 28508865 Free PMC article.

2

A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.

Toor JS, Rao AA, McShan AC, Yarmarkovich M, Nerli S, Yamaguchi K, Madejska AA, Nguyen S, Tripathi S, Maris JM, Salama SR, Haussler D, Sgourakis NG. Toor JS, et al. Among authors: mcshan ac. Front Immunol. 2018 Jan 30;9:99. doi: 10.3389/fimmu.2018.00099. eCollection 2018. Front Immunol. 2018. PMID: 29441070 Free PMC article.

3

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle.

McShan AC, Natarajan K, Kumirov VK, Flores-Solis D, Jiang J, Badstübner M, Toor JS, Bagshaw CR, Kovrigin EL, Margulies DH, Sgourakis NG. McShan AC, et al. Nat Chem Biol. 2018 Aug;14(8):811-820. doi: 10.1038/s41589-018-0096-2. Epub 2018 Jul 9. Nat Chem Biol. 2018. PMID: 29988068 Free PMC article.

4

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling.

Natarajan K, Jiang J, May NA, Mage MG, Boyd LF, McShan AC, Sgourakis NG, Bax A, Margulies DH. Natarajan K, et al. Among authors: mcshan ac. Front Immunol. 2018 Jul 17;9:1657. doi: 10.3389/fimmu.2018.01657. eCollection 2018. Front Immunol. 2018. PMID: 30065727 Free PMC article. Review.

5

De novo design of a non-local β-sheet protein with high stability and accuracy.

Marcos E, Chidyausiku TM, McShan AC, Evangelidis T, Nerli S, Carter L, Nivón LG, Davis A, Oberdorfer G, Tripsianes K, Sgourakis NG, Baker D. Marcos E, et al. Among authors: mcshan ac. Nat Struct Mol Biol. 2018 Nov;25(11):1028-1034. doi: 10.1038/s41594-018-0141-6. Epub 2018 Oct 29. Nat Struct Mol Biol. 2018. PMID: 30374087 Free PMC article.

6

Chemical shift-based methods in NMR structure determination.

Nerli S, McShan AC, Sgourakis NG. Nerli S, et al. Among authors: mcshan ac. Prog Nucl Magn Reson Spectrosc. 2018 Jun-Aug;106-107:1-25. doi: 10.1016/j.pnmrs.2018.03.002. Epub 2018 Mar 11. Prog Nucl Magn Reson Spectrosc. 2018. PMID: 31047599 Free PMC article. Review.

7

An order-to-disorder structural switch activates the FoxM1 transcription factor.

Marceau AH, Brison CM, Nerli S, Arsenault HE, McShan AC, Chen E, Lee HW, Benanti JA, Sgourakis NG, Rubin SM. Marceau AH, et al. Among authors: mcshan ac. Elife. 2019 May 28;8:e46131. doi: 10.7554/eLife.46131. Elife. 2019. PMID: 31134895 Free PMC article.

8

Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection.

McShan AC, Devlin CA, Overall SA, Park J, Toor JS, Moschidi D, Flores-Solis D, Choi H, Tripathi S, Procko E, Sgourakis NG. McShan AC, et al. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25602-25613. doi: 10.1073/pnas.1915562116. Epub 2019 Dec 3. Proc Natl Acad Sci U S A. 2019. PMID: 31796585 Free PMC article.

9

De novo design of a homo-trimeric amantadine-binding protein.

Park J, Selvaraj B, McShan AC, Boyken SE, Wei KY, Oberdorfer G, DeGrado W, Sgourakis NG, Cuneo MJ, Myles DA, Baker D. Park J, et al. Among authors: mcshan ac. Elife. 2019 Dec 19;8:e47839. doi: 10.7554/eLife.47839. Elife. 2019. PMID: 31854299 Free PMC article.

10

Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.

Wei KY, Moschidi D, Bick MJ, Nerli S, McShan AC, Carter LP, Huang PS, Fletcher DA, Sgourakis NG, Boyken SE, Baker D. Wei KY, et al. Among authors: mcshan ac. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7208-7215. doi: 10.1073/pnas.1914808117. Epub 2020 Mar 18. Proc Natl Acad Sci U S A. 2020. PMID: 32188784 Free PMC article.

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